Isopedicin

Catalog No.: A41981
PDE Inhibitor
Isopedicin is a potent phosphodiesterase (PDE) inhibitor that effectively reduces superoxide anion (O2•-) production in formyl-L-methionyl-L-leucyl-L-phenylalanine (FMLP)-activated cells. By inhibiting PDE activity, Isopedicin enhances cyclic AMP (cAMP) formation and promotes protein kinase A (PKA) activity, thereby influencing various intracellular signaling pathways. This compound is suitable for research applications investigating oxidative stress and signaling mechanisms in immune responses.
Grouped product items
Size Price Stock Qty
1mg
$525.00
In stock
Bulk Size
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Free Delivery on orders over $500
Research use only. We do not sell to patients.

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Adooq Products cited in reputable paper
Science VOLUME 380, ISSUE 6663 (2023)
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Cell Vol. 185 Issue 23 p4428-4447.e28
Cell Vol 177, Issue 7, p1933-1947.e25
Cell Vol 156, Issue 5, p857-1114
Nature Volume 622 Issue 7982 (2023)
Nature volume 620, pages890-897 (2023)
Nature volume 610, pages540-546 (2022)
Nature volume 588, pages83-88 (2020)
Nature volume 574, pages268-272 (2019)
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Nature volume 567, pages118-122 (2019)
Nature volume 551, pages639-643 (2017)
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Nature volume 548, pages356-360 (2017)
Nature volume 545, pages187-192 (2017)
Biological Activity
DescriptionIsopedicin is a potent phosphodiesterase (PDE) inhibitor that effectively reduces superoxide anion (O2•-) production in formyl-L-methionyl-L-leucyl-L-phenylalanine (FMLP)-activated cells. By inhibiting PDE activity, Isopedicin enhances cyclic AMP (cAMP) formation and promotes protein kinase A (PKA) activity, thereby influencing various intracellular signaling pathways. This compound is suitable for research applications investigating oxidative stress and signaling mechanisms in immune responses.
Product Information
Catalog NumA41981
FormulaC18H18O6
Molecular Weight330.33
CAS Number4431-42-9
SMILESCOC1=C2C(O[C@H](C3=CC=CC=C3)CC2=O)=C(OC)C(OC)=C1O
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