Isotope-Labeled Compounds

C18(plasm)-18:1 PE-d9 is a deuterated form of C18(plasm)-18:1 phosphatidylethanolamine, serving as a stable isotope used in various biochemical research applications. This compound functions as a reliable internal standard for mass spectrometry, providing accurate quantification in lipidomics and metabolic studies. Its unique isotopic labeling allows for enhanced tracing and analysis of lipid metabolic pathways in cellular systems.

1,10-Decanediol-d20 is the deuterated version of 1,10-decanediol, a diol compound known for its role in the formation of polymeric microparticles (paKG MPs) upon reaction with α-ketoglutarate (aKG). These microparticles facilitate the sustained release of aKG, promoting immunosuppressive responses by modulating dendritic cell metabolism, including reduced glycolysis and mitochondrial respiration. This modulation impacts the expression of key surface markers such as MHC-II and CD86 and influences the frequency of regulatory T cells and T-helper subsets in vitro. 1,10-Decanediol-d20 serves as a critical tool in immunometabolism research and is also useful as a surfactant or stabilizer in nanomaterial synthesis.

2-(2-Iodophenyl)-N,N-dimethylacetamide-d4 is a deuterium-labeled derivative of 2-(2-Iodophenyl)-N,N-dimethylacetamide, functioning as a stable isotope. This compound is utilized in research applications involving isotopic labeling, particularly in studies of metabolic pathways and drug metabolism. Its deuterated form enhances the precision of spectroscopic analyses, making it a valuable reagent for scientists investigating molecular interactions and chemical kinetics.

Fmoc-D-Phe-OH-d5 is a deuterium-labeled derivative of Fmoc-D-phenylalanine. This stable isotope-labeled amino acid serves as a valuable tool in mass spectrometry and tracer studies, facilitating the analysis of protein structure and dynamics. Its incorporation into peptides allows for enhanced sensitivity and specificity in various biological research applications, including studies on protein folding and interactions.

4-Fluorobenzoyl-2,3,5,6-d4 chloride is a deuterium-labeled derivative of 4-Fluorobenzoyl chloride, serving as a stable isotope reagent. This compound is utilized in various analytical applications, particularly in mass spectrometry and isotope labeling studies. It enables precise tracking of molecular interactions and metabolic pathways in biological research.

Taurochenodeoxycholic acid-d4 (TCDCA-d4) is a deuterated derivative of Taurochenodeoxycholic acid, a significant bioactive compound found in animal bile. TCDCA-d4 is utilized as a stable isotope standard in analytical studies. This compound exhibits important biological activities, including the induction of apoptosis, along with pronounced anti-inflammatory and immune regulatory effects, making it valuable for research in various fields such as gastrointestinal biology, hepatology, and pharmacology.

Guanosine-13C10,15N5 hydrate is a stable isotope-labeled form of guanosine, featuring incorporation of 13C and 15N isotopes. This reagent is primarily used in metabolic studies and tracer applications in biochemical research. Its unique isotopic composition enables the precise tracking of metabolic pathways and interactions in cellular systems, facilitating advanced studies in molecular biology and biochemistry.

Fmoc-Pro-OH-15N is a stable isotope-labeled derivative of Fmoc-Pro-OH, featuring a nitrogen-15 (15N) isotope. This compound serves as a valuable tool in NMR spectroscopy and mass spectrometry, enabling precise tracking and quantification of proline residues in complex biological systems. Its applications extend to studies in protein folding, post-translational modifications, and metabolic labeling in research settings.

Sulfamethoxypyridazine-d3 is a deuterium-labeled analog of Sulfamethoxypyridazine, a long-acting sulfonamide antibiotic. This stable isotope is utilized in pharmacokinetic studies and metabolism research to trace and quantify drug behavior in biological systems. Its distinct isotopic labeling aids in differentiating the compound from non-labeled forms in various experimental assays, providing insights into its pharmacodynamics and therapeutic efficacy.

1,3-Dioleoylglycerol-d5 is a deuterated stable isotope of 1,3-Dioleoylglycerol. It serves as a valuable internal standard in lipid metabolism studies, facilitating the analysis of lipid signaling pathways. This reagent enables researchers to trace metabolic processes involving glycerolipids, improving the accuracy of quantification in various biological assays.

1-Bis(4-fluorophenyl)methyl Piperazine-d8 is a deuterium-labeled analog of 1-(Bis(4-fluorophenyl)methyl)piperazine. This stable isotope is primarily utilized in pharmacokinetic studies and tracer applications, facilitating the elucidation of metabolic pathways and interactions. Its unique labeling allows researchers to track compound behavior in complex biological systems effectively.

Benz[a]anthracene-7-acetonitrile-13C2 is a stable isotope-labeled analog of Benz[a]anthracene-7-acetonitrile. This compound is useful for metabolic studies and tracing pathways in biological systems due to its incorporation of carbon-13 isotopes. Researchers can leverage this reagent for advanced applications in environmental monitoring, toxicology, and cancer research, allowing for precise measurements and enhanced analytical accuracy in various experimental setups.

(4-Fluorophenyl)methanol-d4 is a stable isotope-labeled variant of (4-Fluorophenyl)methanol, featuring four deuterium atoms. This compound is valuable for research applications in analytical chemistry, particularly in studies involving isotope labeling techniques, mass spectrometry, and NMR spectroscopy. It facilitates the investigation of metabolic pathways and pharmacokinetic studies, contributing to a deeper understanding of drug behavior and interactions.

Scopine Di(2-thienylglycolate)-d3 is a deuterium-labeled derivative of Scopine Di(2-thienylglycolate) designed for use as a stable isotope. This compound serves as a useful internal standard in mass spectrometry and other analytical techniques, enabling precise quantification in biological and chemical research. Its stability and labeling facilitate detailed studies of metabolic pathways and molecular interactions in various biological systems.

2-((Heptyloxy)carbonyl)benzoic acid-d4 is a deuterium-labeled analogue of 2-((Heptyloxy)carbonyl)benzoic acid, classified as a stable isotope. This compound is primarily utilized in analytical chemistry and biochemistry to trace metabolic pathways and study interactions within biological systems. Its isotopic labeling enhances the sensitivity and accuracy of various labeling techniques, making it an essential tool in chemical research and development.

2-Acetoxy-2-methylpropyl 3-oxobutanoate-d6 is a stable isotope-labeled compound, specifically deuterated at the acetoxy group. This reagent is utilized in metabolic studies and tracer experiments to investigate biochemical pathways and metabolic processes. It serves as an effective tool for researchers examining the dynamics of acetylation and other metabolic reactions in biological systems.

Serinol-d5 is a deuterated analog of serinol, serving as a stable isotope for various biochemical applications. This compound is utilized primarily in isotopic labeling studies, facilitating the investigation of metabolic pathways and molecular interactions in biological research. Its unique isotopic signature allows for enhanced tracking and analysis in mass spectrometry and nuclear magnetic resonance (NMR) experiments.

Dimethyldioctadecylammonium-d74 bromide is a deuterated lipid-based compound that acts as a stable isotope. Its primary mechanism involves the modulation of membrane dynamics and lipid interactions in biological systems. This reagent is essential for studies utilizing mass spectrometry and NMR spectroscopy to investigate lipid metabolism, membrane biology, and drug delivery mechanisms.

Lauryl benzalkonium-d7 chloride is a deuterated form of Lauryl benzalkonium chloride, a cationic surfactant known for its antimicrobial and surfactant properties. This stable isotope labeled compound is useful in various chemical and biological research applications, including studies involving surfactant behavior, membrane interactions, and antimicrobial efficacy. Its deuterium labeling facilitates the investigation of mechanistic pathways and enhances detection sensitivity in analytical methods.

Tetradecanoate-d27 potassium is a deuterium-labeled fatty acid used as a stable isotope in quantitative lipid analysis. This reagent is valuable for studying metabolic pathways involving fatty acid oxidation and synthesis. It serves as a tracer in various biological experiments, aiding in the investigation of lipid metabolism and related disorders.

Methylacetylene-d4 is a stable isotope of Methylacetylene, featuring deuterium labeling. It serves as a versatile click chemistry reagent due to its alkyne functionality, enabling it to participate in copper-catalyzed azide-alkyne cycloaddition (CuAAc) reactions. This reagent is valuable for labeling experiments and elucidating reaction mechanisms in chemical biology and organic synthesis applications.

5α-Pregnan-11β,17α,21-triol-3,20-dione-1,2,4,5-d4 is a stable isotope-labeled derivative of 5α-Pregnan-11β,17α,21-triol-3,20-dione. This compound serves as a valuable internal standard in mass spectrometry applications, facilitating the accurate quantification of steroid hormones in biological samples. It is particularly useful in endocrine research and metabolic studies, enabling detailed investigations of steroid biosynthesis and regulation.

Fmoc-Ala-OH-15N is a 15N-labeled form of Fmoc-Alanine, serving as a stable isotope for research applications. This compound is utilized in NMR studies and isotope labeling experiments, providing valuable insights into peptide synthesis and protein characterization. Its incorporation of the stable nitrogen isotope enhances the accuracy of analytical techniques, facilitating advanced studies in biochemical and pharmaceutical research.

D-Ribose-1,2-13C2 is a stable isotope-labeled form of D-Ribose, serving as a vital component in energy metabolism. It acts as a sugar moiety of ATP and is commonly utilized in metabolic therapy for conditions such as chronic fatigue syndrome and cardiac energy metabolism. Additionally, D-Ribose is involved in protein glycation processes and induces NF-κB-mediated inflammation through a RAGE-dependent mechanism, making it a valuable tool for various biological research applications.

1-Bromodecane-d21 is a stable isotope-labeled version of 1-Bromodecane, featuring deuterium substitution. This compound serves as a valuable internal standard in analytical chemistry and mass spectrometry applications. Its unique isotopic signature enables precise quantification and tracing of organic compounds in complex biological matrices. 1-Bromodecane-d21 is particularly useful in studies involving lipid metabolism and organic synthesis.

Trimethylsilyl N-(trimethylsilyl)acetimidate-d18 is a stable isotope-labeled compound that serves as a deuterium derivative of Trimethylsilyl N-(trimethylsilyl)acetimidate. This reagent is primarily utilized in mass spectrometry for isotopic labeling studies, aiding in the structural elucidation of organic compounds and the quantitative analysis of metabolites. Its stable isotope nature enhances accuracy in analytical methodologies, making it an essential tool for researchers working with complex biological matrices.

N-Nitrosoethylmethylamine-d3 is a deuterated form of N-Nitrosoethylmethylamine, featuring a stable isotope of hydrogen. This compound serves as a useful internal standard in mass spectrometry applications, particularly in toxicological research and environmental monitoring. Its deuterium label enhances the precision of quantitative analyses and metabolite profiling, facilitating studies on the metabolism and toxicokinetics of nitrosamines.

Sodium hexadecyl sulfate-d33 is a deuterium-labeled derivative of sodium hexadecyl sulfate, a surfactant that primarily targets membrane structures and lipid bilayers. It is utilized in research involving lipid dynamics, surfactant activity, and membrane protein interactions. The stable isotope labeling facilitates advanced analytical techniques, such as mass spectrometry, to study the molecular behavior in biological systems.

1-(4-Chlorophenyl)ethanone-d7 is a stable isotope-labeled analog of 1-(4-Chlorophenyl)ethanone, featuring deuterium substitution. This compound serves as a valuable internal standard in analytical chemistry and mass spectrometry applications. It is particularly useful for quantifying metabolites and studying metabolic pathways involving chlorinated phenyl compounds.

3-Bromofluorobenzene-13C6 is a stable isotope-labeled derivative of 3-bromofluorobenzene. This compound is utilized in various analytical and research applications, particularly in tracing studies and metabolic labeling experiments. Its unique isotopic signature allows for enhanced sensitivity in mass spectrometry and nuclear magnetic resonance (NMR) studies, facilitating deeper insights into chemical pathways and interactions.

Miloxacin-d3 is a deuterated form of Miloxacin, functioning as a stable isotope. This modification allows for enhanced tracking and quantification in pharmacokinetic studies. Miloxacin-d3 is valuable in research applications related to antibiotic action, metabolic pathways, and the analysis of drug interactions in various biological systems.

D-Leucine-N-fmoc-d10 is a deuterated derivative of D-Leucine, featuring a stable isotope labeling. This compound is primarily utilized in mass spectrometry and NMR experiments to enhance sensitivity and resolution in analytical studies. It serves as a valuable tool in protein labeling applications, allowing researchers to investigate metabolic pathways and protein interactions with greater precision.

Dimethyl (S)-(4-(methyl-d3)-2-oxooctyl)phosphonate is a deuterated derivative of Dimethyl (S)-(4-(methyl)-2-oxooctyl)phosphonate, functioning as a stable isotope. This compound is utilized in various biochemical research applications, including studies of metabolic pathways and tracing molecular interactions. The incorporation of deuterium enhances the compound's utility in nuclear magnetic resonance (NMR) spectroscopy and mass spectrometry analyses, providing valuable insights into molecular dynamics and behavior in biological systems.

3-Fluorobenzaldehyde 2,4-dinitrophenylhydrazone-d3 is a deuterium-labeled derivative of 3-Fluorobenzaldehyde 2,4-dinitrophenylhydrazone, utilized primarily as a stable isotope in chemical research. This compound serves as an important tool in various analytical applications, including mass spectrometry and metabolic studies, allowing for precise tracking of molecular interactions and pathways. The incorporation of deuterium enhances the resolution of analytical methods, making it valuable for researchers investigating complex chemical systems.

4-Chloro-4'-fluorobutyrophenone-d4 is a stable isotope-labeled derivative of 4-Chloro-1-(4-fluorophenyl)butan-1-one. This compound serves as a valuable internal standard in quantitative analysis, particularly in mass spectrometry applications. It facilitates the accurate detection and quantification of targets in pharmacokinetic studies and metabolic profiling.

Calcitriol (1α,25-Dihydroxyvitamin D3) is a stable isotope labeled with 13C at positions 23, 24, 25, 26, and 27. This compound serves as a valuable tracer in metabolic studies, particularly in vitamin D research. It facilitates investigations into the biological pathways and mechanisms of action of vitamin D, enabling enhanced understanding of its role in calcium metabolism and bone health.

4-Amino-1-pentanol-d4 is a stable isotope-labeled form of 4-Aminopentan-1-ol. This compound is utilized primarily in mass spectrometry and NMR studies, allowing for precise tracking and quantification of metabolic pathways involving amino alcohols. Its deuterium labeling enhances sensitivity and accuracy in analytical applications, making it valuable in chemical and biological research.

2-Ethylhexyl acetate-d17 is a deuterium-labeled derivative of 2-Ethylhexyl acetate, serving as a stable isotope reagent. This compound is utilized in mass spectrometry and tracer studies to track metabolic processes and pathways involving 2-Ethylhexyl acetate in biological systems. Its application extends to various areas of chemical research, including environmental analysis and pharmacokinetics, where precise isotopic labeling enhances data accuracy.

1-Methoxy-2-(2-methoxyethoxy)ethane-d14 is a deuterium-labeled derivative of 1-Methoxy-2-(2-methoxyethoxy)ethane. This stable isotope reagent is commonly used in mass spectrometry and NMR studies to trace metabolic pathways and analyze molecular interactions. Its unique isotopic signature allows for precise quantification and tracking in complex biological systems.

1-Bromo-2,2-dimethylpropane-d2 is a deuterated derivative of 1-Bromo-2,2-dimethylpropane, serving as a stable isotope label. This compound is primarily utilized in studies involving isotopic labeling techniques, enhancing insights into reaction mechanisms, metabolic pathways, and substance tracking in complex biological systems. Its stability and incorporation of deuterium make it suitable for nuclear magnetic resonance (NMR) spectroscopy applications and other analytical studies in chemical research.

2,3,6-Trimethylphenol-d11 is a stable isotope-labeled derivative of 2,3,6-Trimethylphenol. This compound is utilized as a tracer in various analytical applications, including mass spectrometry, to facilitate the study of metabolic pathways and the quantification of phenolic compounds in biological samples. Its unique deuterium labeling enhances sensitivity and accuracy in chemical research, making it a valuable tool in environmental and pharmaceutical studies.

(R)-3-Amino-2-methylpropanoic acid-d3 is a stable isotope-labeled form of the amino acid (R)-3-Amino-2-methylpropanoic acid. This deuterium-labeled compound is used as a tracer in metabolic studies and is ideal for NMR spectroscopy applications. It facilitates investigations into amino acid metabolism and incorporation in biological systems, providing valuable insights in biochemical research.

(Z)-4-(Methoxy-d3)-4-oxobut-2-enoic acid is a deuterium-labeled analog of Monomethyl maleate, serving as a stable isotope for various biochemical studies. This compound is utilized in metabolic tracing and dynamics research, enabling precise investigations of pathways and processes involving malate metabolism. Its unique isotopic labeling makes it valuable in kinetic studies and tracing experiments, providing insights into metabolic profiles and enzyme activity.

N-Tridecanoyl-D-erythro-sphinganine-d7 is a deuterium-labeled form of N-Tridecanoyl-D-erythro-sphinganine, primarily utilized as a stable isotope internal standard in mass spectrometry applications. This compound can be instrumental in quantifying sphingolipids and understanding metabolic pathways involving sphingolipid metabolism. Its isotopic labeling enhances analytical sensitivity and accuracy, providing valuable insights in lipidomics studies.

2,6-Dichlorobiphenyl-2′,3′,4′,5′,6′-d5 is a stable isotope-labeled version of 2,6-Dichloro-1,1'-biphenyl. This compound is utilized in scientific research for tracing studies, providing insight into the environmental behavior and metabolism of chlorinated biphenyls. Its deuterium labeling allows for enhanced detection and quantification in analytical applications, making it an essential tool for researchers studying biochemistry and environmental science.

trans-Trismethoxy Resveratrol-d4 is a deuterium-labeled analog of trans-Trismethoxy Resveratrol, serving as a stable isotope in chemical research. This compound is utilized in studies involving metabolic pathways and pharmacokinetics, providing enhanced accuracy in quantitative analysis. Its unique isotopic signature makes it a valuable tool for tracing and tracking experiments in various biological systems.

p-Azoxyanisole-d6 is a deuterium-labeled derivative of p-Azoxyanisole, serving as a stable isotope for research applications. This compound is commonly utilized in mass spectrometry and isotopic labeling studies, enabling precise tracing and quantification in various biological processes. Its incorporation into experimental designs allows for the investigation of metabolic pathways and the elucidation of compound interactions in complex systems.

CER6-2’S-d9 is a stable isotope-labeled form of CER6-2’S, incorporating deuterium for enhanced tracking in biological systems. This compound is valuable for metabolic studies and can be utilized in various research applications involving isotopic labeling techniques. By providing a stable signature for biochemical pathways, CER6-2’S-d9 aids in elucidating metabolic processes and drug interactions in complex biological matrices.

CVT-2738-d8 is a deuterium-labeled derivative of N-(2,6-Dimethylphenyl)-2-(piperazin-1-yl)acetamide. This stable isotope is utilized in research applications requiring isotopic labeling for enhanced analytical techniques, such as mass spectrometry. The incorporation of deuterium allows for improved tracking and quantification of biological molecules in complex samples, facilitating advanced studies in pharmacokinetics and metabolic pathways.

(Rac)-Aprepitant-d4 is a deuterium-labeled derivative of (Rac)-Aprepitant, primarily utilized as a stable isotope. This compound is instrumental in pharmacokinetic studies, enabling researchers to trace metabolism and distribution in biological systems. Its incorporation into experimental designs can enhance the understanding of drug action and potential therapeutic outcomes in neuropharmacological research.