Tazarotene-13C2,d2

Catalog No.: B14323
Isotope-Labeled Compounds
Tazarotene-13C2,d2 is a stable isotope-labeled derivative of Tazarotene, incorporating both carbon-13 and deuterium. Tazarotene serves as a selective retinoic acid receptor (RAR) agonist, primarily utilized in the treatment of plaque psoriasis and acne vulgaris. This compound can be employed as a click chemistry reagent due to its alkyne functionality, enabling copper-catalyzed azide-alkyne cycloaddition (CuAAc) with azide-containing molecules, which is valuable in chemical biology and medicinal chemistry applications.
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Adooq Products cited in reputable paper
Science VOLUME 380, ISSUE 6663 (2023)
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Cell Vol. 185 Issue 23 p4428-4447.e28
Cell Vol 177, Issue 7, p1933-1947.e25
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Nature Volume 622 Issue 7982 (2023)
Nature volume 620, pages890-897 (2023)
Nature volume 610, pages540-546 (2022)
Nature volume 588, pages83-88 (2020)
Nature volume 574, pages268-272 (2019)
Nature volume 573, pages539-545 (2019)
Nature volume 567, pages118-122 (2019)
Nature volume 551, pages639-643 (2017)
Nature volume 551, pages247-250 (2017)
Nature volume 548, pages356-360 (2017)
Nature volume 545, pages187-192 (2017)
Biological Activity
DescriptionTazarotene-13C2,d2 is a stable isotope-labeled derivative of Tazarotene, incorporating both carbon-13 and deuterium. Tazarotene serves as a selective retinoic acid receptor (RAR) agonist, primarily utilized in the treatment of plaque psoriasis and acne vulgaris. This compound can be employed as a click chemistry reagent due to its alkyne functionality, enabling copper-catalyzed azide-alkyne cycloaddition (CuAAc) with azide-containing molecules, which is valuable in chemical biology and medicinal chemistry applications.
Product Information
Catalog NumB14323
FormulaC1913C2H19D2NO2S
Molecular Weight355.46
CAS Number2703541-64-2
SMILESO=C(C1=CC=C([13C]#[13C]C2=CC=C3C(C(C)(C)CC([2H])([2H])S3)=C2)N=C1)OCC
SynonymsAGN 190168-13C2,d2
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