Isotope-Labeled Compounds

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  1. Stable Isotope

    Dibenzyl Phthalate-d4 is a deuterium-labeled derivative of dibenzyl phthalate, serving as a stable isotope for research applications. This compound is primarily utilized in mass spectrometry and analytical studies for tracing and quantifying substances in biological samples. Its incorporation into biochemical assays allows for enhanced detection capabilities and precise monitoring of metabolic pathways.
  2. Stable Isotope

    4-Fluorobenzoic acid-13C,d4 is a stable isotope-labeled compound featuring both 13C and deuterium modifications. This reagent serves as a valuable intermediate in the synthesis of various hydrazone derivatives, which exhibit antituberculosis activity, and Schiff bases that demonstrate DPPH radical scavenging properties. Its stable isotopic composition makes it suitable for metabolic and pharmacokinetic studies in chemical research applications.
  3. Stable Isotope

    Sudan III-d6 is a deuterium-labeled derivative of Sudan III, a hydrophobic bisazo dye. The incorporation of stable isotopes allows for enhanced tracking and analysis in biological systems. This reagent is applicable in research involving dye transport, metabolic studies, and stability analysis in various experimental settings. Its unique isotopic labeling provides valuable insights into chemical interactions and behaviors in complex biological matrices.
  4. Stable Isotope

    Fluorene-d10 is a deuterated form of fluorene, a polycyclic aromatic hydrocarbon (PAH) known for its role as a precursor in the synthesis of various fluorene derivatives. This stable isotope is valuable in research applications involving the development of fluorene-based dyes and other advanced materials. Its incorporation enhances the tracking and analysis of molecular behavior in complex systems, making it a crucial tool for studies in organic chemistry and material science.
  5. Stable Isotope

    Digoxigenin-d3 is a deuterium-labeled derivative of Digoxigenin, functioning as a stable isotope. This compound serves as a vital labeling agent in situ hybridization applications, notable for its extended shelf life, rapid detection capabilities, and high sensitivity when used with riboprobes. Digoxigenin-d3 is an essential tool for researchers studying gene expression and molecular interactions.
  6. Stable Isotopes

    Indocyanine green-d7 is a deuterium-labeled derivative of the fluorescent dye Indocyanine green. It serves as a stable isotope for tracing applications in medical diagnostics, including the assessment of cardiac output, hepatic function, and liver blood flow dynamics. Additionally, this compound is utilized in ophthalmic angiography, providing valuable insights into vascular health.
  7. Stable Isotope

    Chrysoidine G-d5 hydrochloride is a deuterium-labeled derivative of Chrysoidine G, classified as a stable isotope. This compound serves primarily as a tracer in various chemical research applications, including studies on dye synthesis and textile manufacturing processes. Its concentration can be accurately measured using UV-Vis spectroscopy, making it a valuable tool for analytical and industrial research in dye chemistry.
  8. Stable Isotope

    Pentetic acid-13C5 (Diethylenetriaminepentaacetic acid-13C5) is a stable isotope-labeled derivative of Pentetic acid, recognized for its ability to form robust metal complexes. This compound exhibits significant biological activity in chelating metal ions, which inhibits metal-catalyzed decomposition reactions, particularly in the presence of peroxygen compounds like hydrogen peroxide. Pentetic acid-13C5 is valuable for applications in environmental science, particularly for the removal of heavy metals and dyes from contaminated wastewater through the development of magnetic adsorbents. Its stable carbon isotope labeling allows for advanced tracking and analysis in chemical research studies.
  9. Stable Isotope

    Atazanavir-d9 is a deuterated analog of Atazanavir, a highly selective HIV-1 protease inhibitor. This compound targets the HIV-1 protease enzyme, facilitating the treatment of HIV infections with its ability to inhibit viral replication. Additionally, Atazanavir acts as both a substrate and inhibitor of CYP3A4, as well as an inducer of P-glycoprotein (P-gp). Furthermore, Atazanavir possesses inhibitory activity against SARS-CoV 3CLpro, with an IC50 of 3.49 μM, making it relevant for research in antiviral therapies.
  10. Stable Isotope

    Indene-d3 is a stable isotope-labeled derivative of 1H-Indene, designed for use in various chemical research applications. This compound serves as a valuable internal standard in mass spectrometry and other analytical techniques, enhancing the precision of quantitative analysis. Additionally, Indene-d3 can be utilized in studies involving reaction mechanisms and metabolic pathways, providing insights into the behavior of indene-related compounds in biological systems.
  11. Stable Isotope

    N-Methylpyrrolidone-d3 is a deuterated form of N-Methylpyrrolidone, a polar aprotic solvent widely utilized in chemical synthesis and formulation. This stable isotope serves as a valuable tool in various research applications, including NMR spectroscopy, environmental studies, and metabolic tracing. Its unique properties facilitate enhanced analytical precision in the study of solvent interactions and dynamics in complex mixtures.
  12. Stable Isotope

    Citric acid-d4 trisodium is a deuterium-labeled form of citric acid trisodium, serving as a stable isotope. This compound functions as an acidulant and has been shown to induce apoptosis and promote cell cycle arrest at the G2/M and S phases in HaCaT cells. Additionally, it contributes to oxidative stress in liver cells by reducing the activity of antioxidative enzymes. Citric acid-d4 trisodium is utilized in various research applications, including metabolic studies and the investigation of cellular mechanisms.
  13. Stable Isotope

    N-Myristoylglycine-d2-1 is a deuterium-labeled derivative of N-Myristoylglycine. As a stable isotope, it serves as a crucial tool for metabolic studies and tracer experiments in biological research. This compound aids in elucidating metabolic pathways and assessing the dynamics of fatty acid metabolism in various biological systems. Its unique labeling facilitates precise tracking and quantification in analytical applications.
  14. Stable Isotope

    N-Acetyl-S-(trichlorovinyl)-L-cysteine-d3 is a stable isotope-labeled derivative of N-Acetyl-S-(trichlorovinyl)-L-cysteine. This compound serves as a useful tool for studying the metabolism and biological activity of cysteine derivatives in various biological systems. Its deuterium labeling enables sensitive tracking in metabolic and pharmacokinetic studies, making it valuable for research in toxicology and drug development.
  15. Stable Isotope

    3β,5α,6β-Trihydroxycholestane-d7 is a deuterium-labeled analogue of 3β,5α,6β-Trihydroxycholestane, serving as a stable isotope in research applications. This compound is useful for studying cholesterol metabolism and dynamics in various biological systems, as well as for quantitative analysis in mass spectrometry. Its isotopic labeling enhances detection sensitivity and specificity, making it valuable for biochemical and pharmaceutical research.
  16. Stable Isotope

    BD1063-d8 dihydrochloride is a stable isotope-labeled form of BD1063 dihydrochloride. This reagent serves as a valuable tool for metabolic studies and tracing experiments, enabling researchers to investigate metabolic pathways and interactions within biological systems. Its deuterium labeling enhances the accuracy and reliability of quantitative analyses in various applications, including pharmacokinetics and drug metabolism research.
  17. Stable Isotope

    Desmethylcitalopram-d3 hydrochloride is a deuterated analog of Desmethylcitalopram, serving as a stable isotope. This compound is primarily utilized in pharmacokinetic studies and metabolic research, facilitating the investigation of drug metabolism and bioavailability. Its isotopic labeling enables precise tracking and quantification in biological systems, supporting advancements in therapeutic drug monitoring and personalized medicine.
  18. Stable Isotope

    1-(4-Aza-8-hydroxy-6-oxo)oct-2-en-1-oylimidazole-d3 is a stable isotope-labeled compound essential for precise analytical applications. This deuterium-labeled derivative allows for improved tracking and quantification in mass spectrometry-based experiments. It is particularly useful in pharmacokinetic studies, metabolomics, and investigations of biochemical pathways involving imidazole derivatives.
  19. Stable Isotope

    Dehydro Felodipine-d3 is a deuterium-labeled derivative of Dehydro Felodipine, specifically designed as a stable isotope. This reagent is instrumental for pharmacokinetic studies and metabolic profiling, providing enhanced detection capabilities in mass spectrometry applications. Its unique isotopic signature facilitates accurate quantification of drug levels in biological samples, making it valuable for research in drug metabolism and therapeutic efficacy.
  20. Stable Isotope

    Benzylhydrochlorothiazide-d5 is a deuterated analog of Benzylhydrochlorothiazide, serving as a stable isotope labeled compound. This reagent is primarily utilized in quantitative analysis, facilitating studies in pharmacokinetics and metabolism of thiazide diuretics. Its stable isotope nature allows for precise tracking and differentiation in biological assays and isotope labeling experiments.
  21. Stable Isotope

    Acetanthranil-d3 is a deuterated derivative of Acetanthranil, serving as a stable isotope label. This compound is utilized in various research applications, including metabolic studies and tracer experiments, to accurately monitor the behavior of molecules in biological systems. Its isotopic labeling enables the tracking and quantification of compounds through techniques such as mass spectrometry.
  22. Stable Isotope

    Propanil-d5 is a deuterated form of Propanil, which serves as a contact herbicide primarily utilized in rice cultivation. This stable isotope can be employed in environmental studies and metabolic research to trace herbicide behavior and interactions in biological systems. Its accurate labeling allows for reliable quantification and analysis in various chemical research applications.
  23. Stable Isotope

    Des-p-fluorobenzyl mosapride-d5 is a deuterium-labeled derivative of Des-p-fluorobenzyl mosapride, designed for stable isotope labeling applications. This reagent is valuable in pharmacokinetic studies, metabolic tracking, and as an internal standard for mass spectrometry. Its isotopic labeling facilitates precise quantification and enhances the accuracy of analytical methods in biochemical research.
  24. Stable Isotope

    Estrone 3-methyl ether-d3 is a stable isotope-labeled derivative of Estrone 3-methyl ether, providing enhanced analytical precision in research applications. This compound is primarily used in mass spectrometry and other analytical techniques to trace metabolic pathways and study estrogen-related biological processes. Its stable isotopic nature facilitates accurate quantification in various biological samples, making it a valuable tool in pharmacokinetics and endocrine research.
  25. Stable Isotope

    1-Tetratriacontanol-d4 is a deuterium-labeled form of 1-Tetratriacontanol, serving as a stable isotope for scientific research. This compound is utilized as a tracer in metabolic studies, providing insights into lipid metabolism and dynamics within biological systems. Its isotopic labeling enhances the precision of quantification in analytical methods, making it suitable for various applications in lipid research and pharmacokinetics.
  26. Isotope-Labeled Compound

    N-[3-[3-(Dimethylamino)-1-oxo-2-propenyl]phenyl]-N-ethylacetamide-d3 is a deuterium-labeled derivative of N-[3-[3-(Dimethylamino)-1-oxo-2-propenyl]phenyl]-N-ethylacetamide. This isotope-labeled compound is designed for use in quantitative analysis and metabolic studies, enabling precise tracking of biochemical pathways and drug metabolism. Its application in research facilitates the exploration of pharmacodynamics and pharmacokinetics in various biological systems.
  27. Stable?Isotope

    (±)-Carbinoxamine-d6 is a deuterium-labeled version of (±)-Carbinoxamine, a blood-brain barrier-permeable antagonist of the histamine H1 receptor. This compound effectively blocks histamine's action, alleviating symptoms such as sneezing, rhinitis, and pruritus. In addition, (±)-Carbinoxamine has been shown to inhibit influenza virus entry via endocytosis, targeting early stages of the viral life cycle and reducing viral replication in lung tissues. This reagent is valuable for research on allergic reactions and influenza-related studies.
  28. Stable Isotope

    Cicletanine-d4 hydrochloride is a deuterated form of Cicletanine hydrochloride, serving as a stable isotope labeled compound. This reagent is primarily employed in pharmacokinetic studies and metabolic research to enhance the understanding of Cicletanine's pharmacological properties. Its use in isotopic labeling allows for precise tracking in biological systems, aiding in the elucidation of drug metabolism and pharmacodynamics.
  29. Stable Isotope

    (Rac)-O-Desmethylnaproxen-d3 is a stable isotope-labeled derivative of (Rac)-O-Desmethylnaproxen, marked by the incorporation of deuterium. This compound is utilized in pharmacokinetic studies and metabolic profiling to enhance the accuracy of drug metabolism investigation. Its isotopic labeling allows for sensitive detection and quantification in various biological matrices, making it a valuable tool in drug development and biochemical research.
  30. Stable Isotope

    N-(Acetyl-d3)-S-benzyl-L-cysteine is a deuterium-labeled derivative of N-(Acetyl)-S-benzyl-L-cysteine, designed for stable isotope applications in biochemical research. This compound is utilized to enhance the study of metabolic pathways and protein interactions by providing a distinct mass marker. Its incorporation into experimental designs allows for improved quantification and tracking in various analytical techniques, contributing to advancements in proteomics and metabolic profiling.
  31. Stable Isotope

    (Rac)-trans-N-Methyl Sertraline-d6 hydrochloride is a stable isotope-labeled compound derived from (Rac)-trans-N-Methyl Sertraline hydrochloride. This isotopically enriched reagent is used primarily in pharmacokinetic studies, mass spectrometry, and other analytical applications. Its unique deuterium labeling allows for improved detection and quantification of drug metabolites and interactions in biological systems, making it a valuable tool for researchers in pharmaceutical and biochemical fields.
  32. Stable Isotope

    4-Nitropyridine N-oxide-d4 is a deuterium-labeled analog of 4-Nitropyridine N-oxide, a compound known for its role as a stable isotope in chemical research. This labeled version is particularly useful in studies involving mass spectrometry and tracing applications, providing enhanced analytical accuracy. Its incorporation into various research workflows facilitates the investigation of reaction mechanisms and metabolic pathways within biological systems.
  33. Stable Isotope

    7-Benzyloxy-N-des[[2-(2-hydroxy)ethoxy]ethyl] Quetiapine-d8 is a deuterium-labeled derivative of Quetiapine, a psychopharmacological agent primarily targeting serotonin and dopamine receptors. This stable isotope is utilized in pharmacokinetic studies to accurately track drug metabolism and bioavailability. It serves as a valuable tool for researchers investigating the pharmacodynamics and pharmacogenomics of antipsychotic therapies.
  34. Stable Isotope

    N-Desmethylcarboxy terbinafine methyl ester-d7 is a stable isotope of N-Desmethylcarboxy terbinafine methyl ester, featuring deuterium labeling. This compound serves as a valuable internal standard in mass spectrometry and metabolic studies, facilitating accurate quantification in biological samples. Its applications are relevant in pharmacokinetic research and environmental fate studies, providing insights into the metabolism of terbinafine derivatives.
  35. Stable Isotope

    N-Demethyl Promethazine-d3 (hydrochloride) is a stable isotope-labeled derivative of N-Demethyl Promethazine hydrochloride. This compound serves as a valuable internal standard for quantitative analysis in pharmacokinetic studies and metabolic profiling. Its unique deuterium labeling enhances detection sensitivity and accuracy in various analytical techniques, including mass spectrometry. Researchers utilize this reagent to explore drug metabolism and pharmacodynamics, facilitating deeper insights into the biological pathways of related compounds.
  36. Stable Isotope

    2-Amino-5-Chlorobenzophenone-d5 is a stable isotope-labeled derivative of 2-Amino-5-Chlorobenzophenone. This compound is primarily used as an internal standard in quantitative analytical techniques, enabling precise measurements in various chemical research applications. Its labeling with deuterium enhances mass spectrometric detection sensitivity, making it suitable for studies in pharmacokinetics, toxicology, and metabolic profiling.
  37. Stable Isotope

    Promethazine sulfoxide-d6 is a deuterium-labeled derivative of Promethazine sulfoxide. This stable isotope is utilized in isotopic labeling studies and Metabolic Tracer Research, allowing for precise tracking and quantification in various biological assays. Its unique properties make it a valuable tool in pharmacokinetic studies and the exploration of drug metabolism pathways.
  38. Stable Isotope

    Benzyl 2-(4-(4-fluorobenzylcarbamoyl)-5-hydroxy-1-methyl-6-oxo-1,6-dihydropyrimidin-2-yl)propan-2-ylcarbamate-d3 is a deuterated analogue designed for use as a stable isotope-labeled compound. This reagent serves as a valuable tool in quantitative mass spectrometry and pharmacokinetic studies, allowing for precise tracking of molecular behavior in biological systems. Its unique structure facilitates the investigation of the pharmacological effects and metabolic pathways of pyrimidine derivatives in various biological research applications.
  39. Stable Isotope

    O-Desmethylmetoprolol-d5 is a deuterated analog of O-Desmethylmetoprolol, serving as a stable isotope labeled compound. It is primarily utilized in pharmacokinetic studies and metabolic profiling, allowing for precise tracking of drug metabolism and dynamics. This reagent is essential for applications involving mass spectrometry and other analytical techniques in drug development and pharmacology research.
  40. Stable Isotope

    Dehydro Mefloquine-d5 is a stable isotope-labeled derivative of Dehydro Mefloquine, characterized by the incorporation of five deuterium atoms. This compound serves as a valuable tool in pharmacokinetic studies and metabolic research, enabling precise tracking of drug metabolism and disposition. Its applications extend to the analysis of pharmaceutical compounds in biological matrices, aiding in the elucidation of metabolic pathways and drug interactions.
  41. Stable Isotope

    (Rac)-Cinacalcet-d3 hydrochloride is a deuterium-labeled version of (Rac)-Cinacalcet hydrochloride, serving as a stable isotope. This compound primarily acts as a calcimimetic agent, modulating calcium-sensing receptors and playing a crucial role in the regulation of parathyroid hormone secretion. It is valuable for pharmacokinetic studies and metabolic research, enabling precise tracking of drug metabolism and bioavailability in biological systems.
  42. Stable Isotope

    2-(((4-Methyl-7-oxooctyl)oxy)carbonyl)benzoic acid-d4 is a deuterium-labeled derivative of 2-(((4-Methyl-7-oxooctyl)oxy)carbonyl)benzoic acid. This stable isotope-labeled compound is valuable for research applications that involve the tracking of metabolic pathways and quantitative analysis in various biological systems. Its chemical stability and isotopic labeling support studies in pharmacokinetics and drug metabolism, providing important insights into compound behavior in biological environments.
  43. Stable Isotope

    Methyl 4-(N-(butylcarbamoyl)sulfamoyl)benzoate-d9 is a deuterium-labeled stable isotope compound. It is utilized in research applications requiring isotopic tracing, particularly in pharmacokinetic studies of drug metabolism. This compound aids in understanding the distribution and elimination of sulfamoylbenzoate derivatives in biological systems, facilitating advancements in therapeutic development.
  44. Stable Isotope

    Colchicine-d3 is a deuterium-labeled derivative of colchicine, primarily utilized as a stable isotope for research applications. This compound is valuable in studying colchicine's mechanisms, metabolic pathways, and pharmacokinetics. It supports the investigation of colchicine’s effects in various biological systems and the development of targeted therapies.
  45. Stable Isotope

    7-Methyl-3-methyluric acid-d3 is a deuterated analog of 7-Methyl-3-methyluric acid, serving as a stable isotope. This compound is primarily utilized in various biochemical studies, including metabolic tracking, tracer studies, and the assessment of pharmacokinetics. Its stable isotope labeling offers enhanced detection and quantification capabilities in biological research applications.
  46. Stable Isotope

    rel-(αR,βR)-β-(2,4-Difluorophenyl)-β-hydroxy-α-methyl-1H-1,2,4-triazole-1-butanoic acid-d3 is a stable isotope-labeled version of the compound known for its application in metabolic studies and pharmacokinetic research. The deuterium substitution enhances its reliability in tracing studies without altering its biological activity. This reagent serves as a valuable tool for researchers investigating drug metabolism and molecular interactions in various biological systems.
  47. Stable Isotope

    Chlorpheniramine-d6 maleate is a stable isotope-labeled analog of Chlorpheniramine maleate, featuring deuterium substitution. This reagent is primarily utilized in pharmacokinetic studies and drug metabolism research, allowing for precise tracking and quantification of pharmacological activity in biological systems. Its application in isotopic labeling enhances the accuracy of analytical techniques, contributing to a deeper understanding of drug interactions and effects.
  48. Stable Isotope

    Norquetiapine-d8 is a stable isotope labeled version of Norquetiapine, which acts as a selective inhibitor of HCN1 channels with an IC50 of 13.9 μM. This compound effectively inhibits noradrenaline reuptake and serves as a partial agonist at the 5-HT1A receptor (Ki = 45 nM), while also antagonizing presynaptic α2 (Ki = 237 nM), 5-HT2C (Ki = 107 nM), and 5-HT7 (Ki = 76 nM) receptors. Furthermore, Norquetiapine exhibits state-dependent blockade of the human cardiac sodium channel Nav1.5 and demonstrates partial anti-inflammatory activity in LPS-injected C57BL/6 mice, making it useful for research on depression and inflammation.
  49. Stable Isotope

    (S)-(-)-Verapamil-d3 hydrochloride is a stable isotope-labeled form of (S)-(-)-Verapamil hydrochloride, exhibiting deuterium incorporation. This reagent is utilized in pharmacokinetic studies and metabolic research to trace drug metabolism and distribution. Its ability to provide accurate isotopic measurements makes it valuable for investigations into drug interactions and efficacy.
  50. Stable Isotope

    2-Amino-5-nitrobenzophenone-d5 is a stable isotope-labeled analog of 2-Amino-5-nitrobenzophenone, featuring five deuterium atoms. This compound is primarily utilized in mass spectrometry and isotopic labeling studies to enhance the analysis of complex biological samples. It serves as a useful tool for researchers investigating the metabolism and pharmacokinetics of drug candidates, allowing for precise tracking and quantification of target molecules in various experimental settings.

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