(±)-Carbinoxamine-d6

Catalog No.: B12375
Stable?Isotope
(±)-Carbinoxamine-d6 is a deuterium-labeled version of (±)-Carbinoxamine, a blood-brain barrier-permeable antagonist of the histamine H1 receptor. This compound effectively blocks histamine's action, alleviating symptoms such as sneezing, rhinitis, and pruritus. In addition, (±)-Carbinoxamine has been shown to inhibit influenza virus entry via endocytosis, targeting early stages of the viral life cycle and reducing viral replication in lung tissues. This reagent is valuable for research on allergic reactions and influenza-related studies.
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Research use only. We do not sell to patients.

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Adooq Products cited in reputable paper
Science VOLUME 380, ISSUE 6663 (2023)
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Cell Vol. 185 Issue 23 p4428-4447.e28
Cell Vol 177, Issue 7, p1933-1947.e25
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Nature Volume 622 Issue 7982 (2023)
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Nature volume 574, pages268-272 (2019)
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Nature volume 551, pages639-643 (2017)
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Nature volume 548, pages356-360 (2017)
Nature volume 545, pages187-192 (2017)
Biological Activity
Description(±)-Carbinoxamine-d6 is a deuterium-labeled version of (±)-Carbinoxamine, a blood-brain barrier-permeable antagonist of the histamine H1 receptor. This compound effectively blocks histamine's action, alleviating symptoms such as sneezing, rhinitis, and pruritus. In addition, (±)-Carbinoxamine has been shown to inhibit influenza virus entry via endocytosis, targeting early stages of the viral life cycle and reducing viral replication in lung tissues. This reagent is valuable for research on allergic reactions and influenza-related studies.
Product Information
Catalog NumB12375
FormulaC16H13D6ClN2O
Molecular Weight296.82
CAS Number1216872-59-1
SMILES[2H]C([2H])([2H])N(C([2H])([2H])[2H])CCOC(C1=CC=CC=N1)C2=CC=C(C=C2)Cl
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