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Biological Activity
Ispronicline is a neuronal nicotinic acetylcholine receptor partial agonist. Ispronicline is subtype-selective, binding primarily to the a4b2 subtype. It has antidepressant, nootropic and neuroprotective effects.
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 0.1 mM | 42.67 mL | 213.36 mL | 426.73 mL |
| 0.5 mM | 8.53 mL | 42.67 mL | 85.35 mL |
| 1 mM | 4.27 mL | 21.34 mL | 42.67 mL |
| 5 mM | 0.85 mL | 4.27 mL | 8.53 mL |
*The above data is based on the productmolecular weight 234.341. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.
| Catalog Num | A14183 |
|---|---|
| Actions | Agonist |
| CAS No. | 252870-53-4 |
| Formula | C14H22N2O |
| M. Wt | 234.341 |
| Purity | >98% |
| Synonyms | TC-1734, AZD-3480 |
| SMILES | C[C@@H](C/C=C/C1=CC(=CN=C1)OC(C)C)NC |
| Storage | Store lyophilized at -20ºC, keep desiccated. |
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