IWP-O1

Catalog No.: A16846

PORCN inhibitor

IWP-O1

IWP-O1 Chemical Structure

CAS NO. 2074607-48-8

IWP-O1 is a porcn inhibitor with an EC50 value of 80 pM in a cultured cell reporter assay of Wnt signaling and effectively suppresses the phosphorylation of Dvl2/3 in HeLa cells.

Availability: In stock

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5 mg

Regular Price: $90.00

Special Price $72.00

10 mg

Regular Price: $160.00

Special Price $128.00

50 mg

Regular Price: $600.00

Special Price $480.00

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Biological Activity

IWP-O1 is a porcn inhibitor with an EC50 value of 80 pM in a cultured cell reporter assay of Wnt signaling and effectively suppresses the phosphorylation of Dvl2/3 in HeLa cells.
In vitro DMSO 79 mg/mL (182.66 mM)
Water Insoluble
Ethanol 79 mg/mL (182.66 mM)
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 23.12 mL 115.61 mL 231.22 mL
0.5 mM 4.62 mL 23.12 mL 46.24 mL
1 mM 2.31 mL 11.56 mL 23.12 mL
5 mM 0.46 mL 2.31 mL 4.62 mL

*The above data is based on the productmolecular weight 432.48. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

Catalog Num A16846
Actions Inhibitor
CAS No. 2074607-48-8
Formula C26H20N6O
M. Wt 432.48
Purity >98%
Synonyms IWPO1, IWP O1
SMILES O=C(NC1=NC=C(C2=CC=CC=C2)C=C1)CN3N=NC(C4=CC=NC=C4)=C3C5=CC=CC=C5
Storage

Store lyophilized at -20ºC, keep desiccated.
In lyophilized form, the chemical is stable for 36 months.
In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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