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$0.00 Biological Activity
IWP-O1 is a porcn inhibitor with an EC50 value of 80 pM in a cultured cell reporter assay of Wnt signaling and effectively suppresses the phosphorylation of Dvl2/3 in HeLa cells.
| In vitro | DMSO | 79 mg/mL (182.66 mM) | |
| Water | Insoluble | ||
| Ethanol | 79 mg/mL (182.66 mM) | ||
|
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations. |
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| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 0.1 mM | 23.12 mL | 115.61 mL | 231.22 mL |
| 0.5 mM | 4.62 mL | 23.12 mL | 46.24 mL |
| 1 mM | 2.31 mL | 11.56 mL | 23.12 mL |
| 5 mM | 0.46 mL | 2.31 mL | 4.62 mL |
*The above data is based on the productmolecular weight 432.48. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.
| Catalog Num | A16846 |
|---|---|
| Actions | Inhibitor |
| CAS No. | 2074607-48-8 |
| Formula | C26H20N6O |
| M. Wt | 432.48 |
| Purity | >98% |
| Synonyms | IWPO1, IWP O1 |
| SMILES | O=C(NC1=NC=C(C2=CC=CC=C2)C=C1)CN3N=NC(C4=CC=NC=C4)=C3C5=CC=CC=C5 |
| Storage | Store lyophilized at -20ºC, keep desiccated. |
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