IZTZ-1 is an imidazole-benzothiazole conjugate that functions as a c-MYC inhibitor by stabilizing the G-quadruplex (G4) structure of c-MYC. This stabilization results in the downregulation of c-MYC expression, leading to induction of cell cycle arrest and apoptosis in various cell lines, including B16 melanoma cells. Due to its ability to inhibit cell proliferation and exhibit antitumor activity, IZTZ-1 is a valuable tool for researchers studying melanoma and related cancer pathways.
IZTZ-1 is an imidazole-benzothiazole conjugate that functions as a c-MYC inhibitor by stabilizing the G-quadruplex (G4) structure of c-MYC. This stabilization results in the downregulation of c-MYC expression, leading to induction of cell cycle arrest and apoptosis in various cell lines, including B16 melanoma cells. Due to its ability to inhibit cell proliferation and exhibit antitumor activity, IZTZ-1 is a valuable tool for researchers studying melanoma and related cancer pathways.
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