JBJ-02-112-05 is a potent allosteric inhibitor of the epidermal growth factor receptor (EGFR), specifically targeting mutant forms such as EGFRL858R/T790M with an IC50 of 15 nM. This compound offers a selective approach to inhibit aberrant EGFR activity, making it valuable for research applications in cancer therapeutics and precision oncology. Its oral bioavailability further enhances its utility in preclinical studies of EGFR-driven tumors.
JBJ-02-112-05 is a potent allosteric inhibitor of the epidermal growth factor receptor (EGFR), specifically targeting mutant forms such as EGFRL858R/T790M with an IC50 of 15 nM. This compound offers a selective approach to inhibit aberrant EGFR activity, making it valuable for research applications in cancer therapeutics and precision oncology. Its oral bioavailability further enhances its utility in preclinical studies of EGFR-driven tumors.
This calculator helps you calculate mass of compound based on solution concentration, volume and molecular weight in a specific solution using the formula:
