JBPOS-0101

Catalog No.: A78399
Neuroprotective Agent
JBPOS-0101 is a phenyl carbamate compound that acts as a neuroprotective agent. This compound has demonstrated neuroprotective and antiepileptic effects, specifically attenuating the accumulation of amyloid-beta (Aβ) in the brains of 5XFAD mouse models. Additionally, JBPOS-0101 has been shown to rescue deficits in learning and memory, making it a valuable tool for research into neurological diseases, including Alzheimer's disease.
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Research use only. We do not sell to patients.

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Adooq Products cited in reputable paper
Science VOLUME 380, ISSUE 6663 (2023)
Science VOLUME 369, ISSUE 6510 (2020)
Science VOLUME 356, ISSUE 6336 (2017)
Cell Vol. 185 Issue 23 p4428-4447.e28
Cell Vol 177, Issue 7, p1933-1947.e25
Cell Vol 156, Issue 5, p857-1114
Nature Volume 622 Issue 7982 (2023)
Nature volume 620, pages890-897 (2023)
Nature volume 610, pages540-546 (2022)
Nature volume 588, pages83-88 (2020)
Nature volume 574, pages268-272 (2019)
Nature volume 573, pages539-545 (2019)
Nature volume 567, pages118-122 (2019)
Nature volume 551, pages639-643 (2017)
Nature volume 551, pages247-250 (2017)
Nature volume 548, pages356-360 (2017)
Nature volume 545, pages187-192 (2017)
Biological Activity
DescriptionJBPOS-0101 is a phenyl carbamate compound that acts as a neuroprotective agent. This compound has demonstrated neuroprotective and antiepileptic effects, specifically attenuating the accumulation of amyloid-beta (Aβ) in the brains of 5XFAD mouse models. Additionally, JBPOS-0101 has been shown to rescue deficits in learning and memory, making it a valuable tool for research into neurological diseases, including Alzheimer's disease.
Product Information
Catalog NumA78399
FormulaC10H12ClNO3
Molecular Weight229.66
CAS Number1353949-71-9
SMILESNC(O[C@@H](C)[C@H](C1=C(C=CC=C1)Cl)O)=O
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