Biological Activity
Jervine is a naturally occuring steroidal alkaloid that causes cyclopia by blocking sonic hedgehog(Shh) signaling; Jervine is an inhibitor of Smo.
Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
---|---|---|---|
0.1 mM | 23.5 mL | 117.48 mL | 234.96 mL |
0.5 mM | 4.7 mL | 23.5 mL | 46.99 mL |
1 mM | 2.35 mL | 11.75 mL | 23.5 mL |
5 mM | 0.47 mL | 2.35 mL | 4.7 mL |
*The above data is based on the productmolecular weight 425.6. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.
Catalog Num | A16221 |
---|---|
Actions | Inhibitor |
M. Wt | 425.6 |
Formula | C27H39NO3 |
Solubility | DMSO |
Purity | >98% |
Storage | at -20°C 3 years Powder |
CAS No. | 469-59-0 |
Synonyms | 11-Ketocyclopamine |
SMILES | CC1CC2C(C(C3(O2)CCC4C5CC=C6CC(CCC6(C5C(=O)C4=C3C)C)O)C)NC1 |
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