JIB-04

Catalog No.: A13806

Histone Demethylase inhibitor

JIB-04

JIB-04 Chemical Structure

CAS NO. 199596-05-9

JIB-04 is a pan-selective Jumonji histone demethylase inhibitor with IC50 of 230, 340, 855, 445, 435, 1100, and 290 nM for JARID1A, JMJD2E, JMJD3, JMJD2A, JMJD2B, JMJD2C, and JMJD2D, respectively.

Availability: In stock

Package Price Qty
25 mg

Regular Price: $120.00

Special Price $108.00

50 mg

Regular Price: $200.00

Special Price $180.00

100 mg

Regular Price: $350.00

Special Price $315.00

10mM * 1mL in DMSO

Regular Price: $90.00

Special Price $81.00

Warning Products are for laboratory research use only. Not for human use. We do not sell to patients.

Biological Activity

JIB-04 is a pan-selective Jumonji histone demethylase inhibitor with IC50 of 230, 340, 855, 445, 435, 1100, and 290 nM for JARID1A, JMJD2E, JMJD3, JMJD2A, JMJD2B, JMJD2C, and JMJD2D, respectively.
In vitro DMSO 25 mg/mL heating (80.96 mM)
Water <1 mg/mL (<1 mM)
Ethanol <1 mg/mL (<1 mM)
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 32.39 mL 161.94 mL 323.88 mL
0.5 mM 6.48 mL 32.39 mL 64.78 mL
1 mM 3.24 mL 16.19 mL 32.39 mL
5 mM 0.65 mL 3.24 mL 6.48 mL

*The above data is based on the productmolecular weight 308.76. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

Catalog Num A13806
Actions Inhibitor
M. Wt 308.76
Formula C17H13ClN4
Solubility DMSO
Purity >98%
Storage at -20°C 3 years Powder
CAS No. 199596-05-9
Synonyms NSC 693627, JIB04
SMILES C1=CC=C(C=C1)/C(=N\NC2=NC=C(C=C2)Cl)/C3=CC=CC=N3

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