(+)-JJ-74-138 is a novel non-competitive antagonist of the androgen receptor (AR) that demonstrates significant potency against Enzalutamide-resistant castration-resistant prostate cancer (CRPC). This compound effectively inhibits AR signaling, making it a valuable tool for investigating alternative therapeutic strategies in prostate cancer research. Its application in preclinical studies may provide insights into overcoming resistance mechanisms in androgen-targeted therapies.
(+)-JJ-74-138 is a novel non-competitive antagonist of the androgen receptor (AR) that demonstrates significant potency against Enzalutamide-resistant castration-resistant prostate cancer (CRPC). This compound effectively inhibits AR signaling, making it a valuable tool for investigating alternative therapeutic strategies in prostate cancer research. Its application in preclinical studies may provide insights into overcoming resistance mechanisms in androgen-targeted therapies.
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