JNJ-10397049

Catalog No.: A14104

OX2 receptor antagonist

JNJ-10397049

JNJ-10397049 Chemical Structure

CAS NO. 708275-58-5

JNJ-10397049 is a potent, selective, and bioavailable antagonist of the orexin-2 receptor (OX2R) (KB = 4.5 nM for OX2R versus 1.1 μM for OX1R).

Availability: In stock

Package Price Qty
10 mg
$90.00
25 mg
$200.00
50 mg
$300.00
Warning Products are for laboratory research use only. Not for human use. We do not sell to patients.

Biological Activity

JNJ-10397049 is a potent, selective, and bioavailable antagonist of the orexin-2 receptor (OX2R) (KB = 4.5 nM for OX2R versus 1.1 μM for OX1R).
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 20.65 mL 103.26 mL 206.53 mL
0.5 mM 4.13 mL 20.65 mL 41.31 mL
1 mM 2.07 mL 10.33 mL 20.65 mL
5 mM 0.41 mL 2.07 mL 4.13 mL

*The above data is based on the productmolecular weight 484.2. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

Chemical Properties

Catalog Num A14104
Actions Antagonist
M. Wt 484.2
Formula C19H20Br2N2O3
Solubility DMSO
Purity >98%
Storage at -20°C 3 years Powder
CAS No. 708275-58-5
Synonyms JNJ 10397049, JNJ10397049
SMILES CC1(OC[[email protected]@H]([[email protected]@H](O1)C2=CC=CC=C2)NC(=O)NC3=C(C=C(C=C3)Br)Br)C

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