JNJ-20788560 is a selective, orally active agonist of the delta opioid receptor (DOR) with a high affinity of 2.0 nM, as demonstrated in rat brain cortex binding assays. This compound exhibits potent antihyperalgesic properties and is notable for its lack of respiratory depression, pharmacologic tolerance, and physical dependence. JNJ-20788560 is suitable for research applications focused on the mechanisms underlying inflammatory hyperalgesia and pain relief strategies.
JNJ-20788560 is a selective, orally active agonist of the delta opioid receptor (DOR) with a high affinity of 2.0 nM, as demonstrated in rat brain cortex binding assays. This compound exhibits potent antihyperalgesic properties and is notable for its lack of respiratory depression, pharmacologic tolerance, and physical dependence. JNJ-20788560 is suitable for research applications focused on the mechanisms underlying inflammatory hyperalgesia and pain relief strategies.
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