JNJ-26146900

Catalog No.: A85034
Androgen Receptor Antagonist
JNJ-26146900 is a potent nonsteroidal androgen receptor antagonist, exhibiting a Ki value of 400 nM for the rat androgen receptor. This compound is effective in reducing prostate tumor size and preventing bone loss, making it valuable for cancer research applications. JNJ-26146900 serves as a critical tool for investigating the roles of androgen receptors in prostate cancer progression and therapeutic strategies.
Grouped product items
Size Price Stock Qty
25mg
$1,405.00
In stock
50mg
$1,790.00
In stock
100mg
$2,240.00
In stock
Bulk Size
Bulk Discount
Free Delivery on orders over $500
Research use only. We do not sell to patients.

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Adooq Products cited in reputable paper
Science VOLUME 380, ISSUE 6663 (2023)
Science VOLUME 369, ISSUE 6510 (2020)
Science VOLUME 356, ISSUE 6336 (2017)
Cell Vol. 185 Issue 23 p4428-4447.e28
Cell Vol 177, Issue 7, p1933-1947.e25
Cell Vol 156, Issue 5, p857-1114
Nature Volume 622 Issue 7982 (2023)
Nature volume 620, pages890-897 (2023)
Nature volume 610, pages540-546 (2022)
Nature volume 588, pages83-88 (2020)
Nature volume 574, pages268-272 (2019)
Nature volume 573, pages539-545 (2019)
Nature volume 567, pages118-122 (2019)
Nature volume 551, pages639-643 (2017)
Nature volume 551, pages247-250 (2017)
Nature volume 548, pages356-360 (2017)
Nature volume 545, pages187-192 (2017)
Biological Activity
DescriptionJNJ-26146900 is a potent nonsteroidal androgen receptor antagonist, exhibiting a Ki value of 400 nM for the rat androgen receptor. This compound is effective in reducing prostate tumor size and preventing bone loss, making it valuable for cancer research applications. JNJ-26146900 serves as a critical tool for investigating the roles of androgen receptors in prostate cancer progression and therapeutic strategies.
Product Information
Catalog NumA85034
FormulaC15H15F3N2O3S
Molecular Weight360.35
CAS Number868691-50-3
SMILESN#CC1=CC2=C(C=C1C(F)(F)F)NC([C@@](O)(CS(=O)(CC)=O)C)=C2
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