JNJ-42165279 dihydrochloride

Catalog No.: A74671
FAAH Inhibitor
JNJ-42165279 dihydrochloride is a selective inhibitor of fatty acid amide hydrolase (FAAH) with an IC50 of 70 nM for human FAAH and 313 nM for rat FAAH. This compound enhances endocannabinoid levels by preventing the breakdown of fatty acid amides, which can lead to increased pain relief and anti-inflammatory effects. JNJ-42165279 is utilized in research applications focusing on pain management, neuroprotection, and the modulation of the endocannabinoid system.
Grouped product items
Size Price Stock Qty
25mg
$1,275.00
In stock
50mg
$1,625.00
In stock
100mg
$2,000.00
In stock
Bulk Size
Bulk Discount
Free Delivery on orders over $500
Research use only. We do not sell to patients.

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Adooq Products cited in reputable paper
Science VOLUME 380, ISSUE 6663 (2023)
Science VOLUME 369, ISSUE 6510 (2020)
Science VOLUME 356, ISSUE 6336 (2017)
Cell Vol. 185 Issue 23 p4428-4447.e28
Cell Vol 177, Issue 7, p1933-1947.e25
Cell Vol 156, Issue 5, p857-1114
Nature Volume 622 Issue 7982 (2023)
Nature volume 620, pages890-897 (2023)
Nature volume 610, pages540-546 (2022)
Nature volume 588, pages83-88 (2020)
Nature volume 574, pages268-272 (2019)
Nature volume 573, pages539-545 (2019)
Nature volume 567, pages118-122 (2019)
Nature volume 551, pages639-643 (2017)
Nature volume 551, pages247-250 (2017)
Nature volume 548, pages356-360 (2017)
Nature volume 545, pages187-192 (2017)
Biological Activity
DescriptionJNJ-42165279 dihydrochloride is a selective inhibitor of fatty acid amide hydrolase (FAAH) with an IC50 of 70 nM for human FAAH and 313 nM for rat FAAH. This compound enhances endocannabinoid levels by preventing the breakdown of fatty acid amides, which can lead to increased pain relief and anti-inflammatory effects. JNJ-42165279 is utilized in research applications focusing on pain management, neuroprotection, and the modulation of the endocannabinoid system.
Product Information
Catalog NumA74671
FormulaC18H19Cl3F2N4O3
Molecular Weight483.72
CAS Number1346528-51-5
SMILESO=C(N1CCN(CC2=CC=C(OC(F)(F)O3)C3=C2)CC1)NC4=C(Cl)C=CN=C4.[H]Cl.[H]Cl
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