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JSH 23


NF-κB inhibitor

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Catalog No. A14142

Availability:Stock in USAIn stock

Product Name Catalog No. Price Qty
JSH 23 5mg A14142-5

Regular Price: €80.75

Special Price: €72.68

JSH 23 10mg A14142-10

Regular Price: €152.00

Special Price: €136.80

JSH 23 25mg A14142-25

Regular Price: €304.00

Special Price: €273.60

JSH 23 10mM * 1mL in DMSO A14142-10mM-D

Regular Price: €90.25

Special Price: €81.23

Products are for laboratory research use only. Not for human use. We do not sell to patients.

Quick Overview

JSH 23 is an inhibitor of NF-κB, blocking its translocation into the nucleus (IC50 = 7.1 μM).

JSH 23

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Publications citing Adooq Products
JSH 23  Citations (1)
  • Yu N, .et al. Low-Dose Radiation Promotes Dendritic Cell Migration and IL-12 Production via the ATM/NF-KappaB Pathway, Radiat Res, 2018, Apr;189(4):409-417 PMID: 29420126

Chemical Information

Catalog Num A14142
Actions Inhibitor
M. Wt 240.3
Formula C16H20N2
Solubility DMSO
Purity >98%
Storage at -20°C 3 years Powder
CAS No. 749886-87-1
Synonyms JSH-23,JSH23, NF??B Activation Inhibitor II

Biological Activity

JSH 23 is an inhibitor of NF-κB, blocking its translocation into the nucleus (IC50 = 7.1 μM).


Solubility (25°C)* In vitro DMSO 48 mg/mL (199.71 mM)
Water <1 mg/mL (<1 mM)
Ethanol 20 mg/mL (83.21 mM)
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.

Preparing Stock Solutions

Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 41.61 mL 208.07 mL 416.15mL
0.5 mM 8.32 mL 41.61 mL 83.23 mL
1 mM 4.16 mL 20.81 mL 41.61 mL
5 mM 0.83 mL 4.16 mL 8.32 mL

*The above data is based on the productmolecular weight 240.3. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

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