JSH 23

Catalog No.: A14142

NF-κB inhibitor

JSH 23

JSH 23 Chemical Structure

CAS NO. 749886-87-1

JSH 23 is an inhibitor of NF-kB, blocking its translocation into the nucleus (IC50 = 7.1 uM)

Availability: In stock

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5 mg

Regular Price: $85.00

Special Price $68.00

10 mg

Regular Price: $160.00

Special Price $128.00

25 mg

Regular Price: $320.00

Special Price $256.00

10mM * 1mL in DMSO

Regular Price: $95.00

Special Price $76.00

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Warning Products are for laboratory research use only. Not for human use. We do not sell to patients.
  • Yu N, .et al. Low-Dose Radiation Promotes Dendritic Cell Migration and IL-12 Production via the ATM/NF-KappaB Pathway, Radiat Res, 2018, Apr;189(4):409-417 PMID: 29420126

Biological Activity

JSH 23 is an inhibitor of NF-kB, blocking its translocation into the nucleus (IC50 = 7.1 uM)
In vitro DMSO 41 mg/mL (170.59 mM)
Water Insoluble
Ethanol 17 mg/mL (70.73 mM)
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 41.61 mL 208.07 mL 416.15 mL
0.5 mM 8.32 mL 41.61 mL 83.23 mL
1 mM 4.16 mL 20.81 mL 41.61 mL
5 mM 0.83 mL 4.16 mL 8.32 mL

*The above data is based on the productmolecular weight 240.3. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

Catalog Num A14142
Actions Inhibitor
CAS No. 749886-87-1
Formula C16H20N2
M. Wt 240.3
Purity >98%
Synonyms JSH-23,JSH23, NF??B Activation Inhibitor II
SMILES CC1=CC(=C(C=C1)NCCCC2=CC=CC=C2)N
Storage

Store lyophilized at -20ºC, keep desiccated.
In lyophilized form, the chemical is stable for 36 months.
In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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