JWG-071

Name: JWG-071
Brand: Adooq Bioscience
SKU: A24199
Rating: 5 (288 reviews)

Catalog No.: A24199

ERK5 Probe

JWG-071 is a kinase-selective chemical probe targeting ERK5, with an IC50 of 88 nM. It also exhibits inhibitory activity against LRRK2, with an IC50 of 109 nM, making it a valuable tool for studying ERK5- and LRRK2-related signaling pathways.

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Grouped product items
Size	Price	Stock
5mg	$63.00	In stock
10mg	$109.00	In stock
50mg	$322.00	In stock
100mg	$630.00	In stock
Bulk Size	Bulk Discount

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Biological Activity

Description	JWG-071 is a kinase-selective chemical probe targeting ERK5, with an IC50 of 88 nM. It also exhibits inhibitory activity against LRRK2, with an IC50 of 109 nM, making it a valuable tool for studying ERK5- and LRRK2-related signaling pathways.

Product Information

Catalog Num	A24199
Formula	C34H44N8O3
Molecular Weight	612.75
CAS Number	2250323-50-1
SMILES	COC1=CC(C(N2CCC(N3CCN(C)CC3)CC2)=O)=CC=C1NC4=NC=C(N(C)C5=O)C(N(C6=CC=CC=C65)C(C)CC)=N4
Storage	Store lyophilized at -20ºC, keep desiccated. In lyophilized form, the chemical is stable for 36 months. In solution, store at -20ºC and use within 1 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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