K 858

Catalog No.: A15844

Kinesin Eg5 inhibitor

K 858

K 858 Chemical Structure

CAS NO. 72926-24-0

K 858 is a selective ATP-uncompetitive mitotic kinesin Eg5 inhibitor with IC50 value of 1.3 uM.

Availability: In stock

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10 mg

Regular Price: $81.00

Special Price $64.80

25 mg

Regular Price: $162.00

Special Price $129.60

50 mg

Regular Price: $243.00

Special Price $194.40

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Biological Activity

K 858 is a selective ATP-uncompetitive mitotic kinesin Eg5 inhibitor with IC50 value of 1.3 uM.
In vitro DMSO 53 mg/mL (191.1 mM)
Water Insoluble
Ethanol 4 mg/mL (14.42 mM)
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 36.06 mL 180.28 mL 360.57 mL
0.5 mM 7.21 mL 36.06 mL 72.11 mL
1 mM 3.61 mL 18.03 mL 36.06 mL
5 mM 0.72 mL 3.61 mL 7.21 mL

*The above data is based on the productmolecular weight 277.34. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

Catalog Num A15844
Actions Inhibitor
CAS No. 72926-24-0
Formula C13H15N3O2S
M. Wt 277.34
Purity >98%
Synonyms K-858, K858
SMILES CC(NC1=NN(C(C)=O)C(C2=CC=CC=C2)(C)S1)=O
Storage

Store lyophilized at -20ºC, keep desiccated.
In lyophilized form, the chemical is stable for 36 months.
In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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