K-Ras(G12C) inhibitor 12

Name: K-Ras(G12C) inhibitor 12
Brand: Adooq Bioscience
SKU: A14227
Rating: 5 (288 reviews)

Catalog No.: A14227

K-Ras(G12C) inhibitor

K-Ras(G12C) inhibitor 12 is an allosteric inhibitor of oncogenic K-Ras(G12C).

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K-Ras(G12C) inhibitor 12 1469337-95-8 K-Ras(G12C) inhibitor

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Grouped product items
Size	Price	Stock
1mg	$35.00	In stock
5mg	$90.00	In stock
10mg	$140.00	In stock
25mg	$255.00	In stock
50mg	$390.00	In stock
100mg	$590.00	In stock
*10mM 1mL in DMSO**	$100.00	In stock
Bulk Size	Bulk Discount

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Data Sheet SDS

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Biological Activity

Description

K-Ras(G12C) inhibitor 12 is an allosteric inhibitor of oncogenic K-Ras(G12C).

Targets

Target	Value

Product Information

Catalog Num	A14227
Formula	C15H17ClIN3O3
Molecular Weight	449.67
CAS Number	1469337-95-8
SMILES	C=CC(=O)N1CCN(CC1)C(=O)CNC2=CC(=C(C=C2O)Cl)I
Storage	Store lyophilized at -20ºC, keep desiccated. In lyophilized form, the chemical is stable for 36 months. In solution, store at -20ºC and use within 1 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

Solubility

In vitro	DMSO	24 mg/mL (53.37 mM)
	Water	Insoluble
	Ethanol	Insoluble
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.

Preparing Stock Solutions

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
0.1 mM	22.24 mL	111.19 mL	222.39 mL
0.5 mM	4.45 mL	22.24 mL	44.48 mL
1 mM	2.22 mL	11.12 mL	22.24 mL
5 mM	0.44 mL	2.22 mL	4.45 mL

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Mass (mg) = Concentration (mM) × Volume (mL) × Molecular Weight (g/mol)

* Please check COA/MSDS for correct molecular weight.

Calculate the dilution required to prepare a stock solution.
This equation is commonly abbreviated as: C₁V₁ = C₂V₂