K-Ras(G12C) inhibitor 6

Name: K-Ras(G12C) inhibitor 6
Brand: Adooq Bioscience
SKU: A14103
Rating: 5 (288 reviews)

Catalog No.: A14103

K-Ras(G12C) inhibitor

K-Ras(G12C) inhibitor 6 is an irreversible inhibitor of oncogenic K-Ras(G12C), subverting the native nucleotide preference to favour GDP over GTP.

Skip to the end of the images gallery

K-Ras(G12C) inhibitor 6 2060530-16-5 K-Ras(G12C) inhibitor

Skip to the beginning of the images gallery

Grouped product items
Size	Price	Stock
1mg	$50.00	In stock
2mg	$75.00	In stock
5mg	$130.00	In stock
10mg	$175.00	In stock
25mg	$345.00	In stock
50mg	$595.00	In stock
100mg	$975.00	In stock
*10mM 1mL in DMSO**	$130.00	In stock
Bulk Size	Bulk Discount

Bulk Inquiry

Notify me when the price drops

Free Delivery on orders over $500

Research use only. We do not sell to patients.

Data Sheet SDS

Loading distributor info...

Adooq Products cited in reputable paper

Biological Activity

Description	K-Ras(G12C) inhibitor 6 is an irreversible inhibitor of oncogenic K-Ras(G12C), subverting the native nucleotide preference to favour GDP over GTP.

Product Information

Catalog Num	A14103
Formula	C17H22Cl2N2O3S
Molecular Weight	405.34
CAS Number	2060530-16-5
SMILES	C1CN(CCC1NC(=O)CCCS)C(=O)COC2=C(C=C(C=C2)Cl)Cl
Storage	Store lyophilized at -20ºC, keep desiccated. In lyophilized form, the chemical is stable for 36 months. In solution, store at -20ºC and use within 1 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

Solubility

In vitro	DMSO	75 mg/mL (185.03 mM)
	Water	Insoluble
	Ethanol	28 mg/mL (69.08 mM)
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.

Preparing Stock Solutions

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
0.1 mM	24.67 mL	123.35 mL	246.71 mL
0.5 mM	4.93 mL	24.67 mL	49.34 mL
1 mM	2.47 mL	12.34 mL	24.67 mL
5 mM	0.49 mL	2.47 mL	4.93 mL

Useful Calculator

This calculator helps you calculate mass of compound based on solution concentration, volume and molecular weight in a specific solution using the formula:

Mass (mg) = Concentration (mM) × Volume (mL) × Molecular Weight (g/mol)

* Please check COA/MSDS for correct molecular weight.

Calculate the dilution required to prepare a stock solution.
This equation is commonly abbreviated as: C₁V₁ = C₂V₂