Kaliotoxin (1-37)

Catalog No.: A68264
Potassium Channel Blocker
Kaliotoxin (1-37) is a calcium-dependent potassium channel blocker derived from the venom of the scorpion Androctonus mauretanicus. This peptide demonstrates potent inhibition of potassium channels, making it a valuable tool for research into neuronal excitability and muscle contraction mechanisms. It is widely utilized in studies exploring ion channel function, neurophysiology, and potential therapeutic applications in cardiac and neurological disorders.
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Research use only. We do not sell to patients.

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Adooq Products cited in reputable paper
Science VOLUME 380, ISSUE 6663 (2023)
Science VOLUME 369, ISSUE 6510 (2020)
Science VOLUME 356, ISSUE 6336 (2017)
Cell Vol. 185 Issue 23 p4428-4447.e28
Cell Vol 177, Issue 7, p1933-1947.e25
Cell Vol 156, Issue 5, p857-1114
Nature Volume 622 Issue 7982 (2023)
Nature volume 620, pages890-897 (2023)
Nature volume 610, pages540-546 (2022)
Nature volume 588, pages83-88 (2020)
Nature volume 574, pages268-272 (2019)
Nature volume 573, pages539-545 (2019)
Nature volume 567, pages118-122 (2019)
Nature volume 551, pages639-643 (2017)
Nature volume 551, pages247-250 (2017)
Nature volume 548, pages356-360 (2017)
Nature volume 545, pages187-192 (2017)
Biological Activity
DescriptionKaliotoxin (1-37) is a calcium-dependent potassium channel blocker derived from the venom of the scorpion Androctonus mauretanicus. This peptide demonstrates potent inhibition of potassium channels, making it a valuable tool for research into neuronal excitability and muscle contraction mechanisms. It is widely utilized in studies exploring ion channel function, neurophysiology, and potential therapeutic applications in cardiac and neurological disorders.
Product Information
Catalog NumA68264
FormulaC165H271N53O48S8
Molecular Weight4018.82
CAS Number150769-72-5
Sequence shorteningGVEINVKCSGSPQCLKPCKDAGMRFGKCMNRKCHCTP (Disulfide bridge: Cys8-Cys28;Cys14-Cys33;Cys18-Cys35)
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