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Kalopanaxsaponin I

Catalog No.: B18647
Oleanane-Type Triterpenoid
Kalopanaxsaponin I is an oleanane-type triterpenoid derived from the fruits of Stauntonia brachyanthera. It effectively inhibits LPS-induced nitric oxide production in macrophages, exhibiting an IC50 of 80.25 μM. This compound is valuable for studying inflammatory responses and macrophage activation in various biological research applications.
Kalopanaxsaponin I 843668-13-3 Oleanane-Type Triterpenoid
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Research use only. We do not sell to patients.
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Adooq Products cited in reputable paper
Science VOLUME 380, ISSUE 6663 (2023)
Science VOLUME 369, ISSUE 6510 (2020)
Science VOLUME 356, ISSUE 6336 (2017)
Cell Vol. 185 Issue 23 p4428-4447.e28
Cell Vol 177, Issue 7, p1933-1947.e25
Cell Vol 156, Issue 5, p857-1114
Nature Volume 622 Issue 7982 (2023)
Nature volume 620, pages890-897 (2023)
Nature volume 610, pages540-546 (2022)
Nature volume 588, pages83-88 (2020)
Nature volume 574, pages268-272 (2019)
Nature volume 573, pages539-545 (2019)
Nature volume 567, pages118-122 (2019)
Nature volume 551, pages639-643 (2017)
Nature volume 551, pages247-250 (2017)
Nature volume 548, pages356-360 (2017)
Nature volume 545, pages187-192 (2017)
Biological Activity
DescriptionKalopanaxsaponin I is an oleanane-type triterpenoid derived from the fruits of Stauntonia brachyanthera. It effectively inhibits LPS-induced nitric oxide production in macrophages, exhibiting an IC50 of 80.25 μM. This compound is valuable for studying inflammatory responses and macrophage activation in various biological research applications.
Product Information
Catalog NumB18647
FormulaC69H112O34
Molecular Weight1485.61
CAS Number843668-13-3
SMILESOC[C@H]([C@H]([C@@H]([C@H]1O)O)O[C@H]2[C@@H]([C@@H]([C@H]([C@@H](O2)C)O)O)O)O[C@H]1OC[C@H]([C@H]([C@@H]([C@H]3O)O)O)O[C@H]3OC([C@]45[C@](CC(C)(CC5)C)([H])C6=CC[C@@]([C@@]7([C@@]([C@@](C)([C@H](CC7)O[C@H]8[C@@H]([C@H]([C@H](CO8)O)O)O[C@H]9[C@@H]([C@@H]([C@H]([C@@H](O9)C)O)O[C@H]%10[C@@H]([C@H]([C@@H](CO%10)O[C@H]%11[C@@H]([C@H]([C@@H](CO%11)O)O)O)O)O)O)CO)([H])CC%12)C)([H])[C@]%12(C)[C@@]6(CC4)C)=O
SynonymsSeptemloside I
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