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KCa2 channel modulator 1

Catalog No.: A68139
KCa2 Channel Modulator
KCa2 Channel Modulator 1 is a potent subtype-selective positive modulator specifically targeting KCa2 channels. It enhances the activity of human KCa2.3 channels with an EC50 of 0.19 μM, and also exhibits activity on rat KCa2.2 channels with an EC50 of 0.99 μM. This compound is valuable for research applications focusing on calcium-activated potassium channels and their roles in various physiological processes.
KCa2 channel modulator 1 1019106-73-0 KCa2 Channel Modulator
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Size Price Stock Qty
25mg
$1,275.00
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50mg
$1,625.00
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100mg
$2,000.00
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Research use only. We do not sell to patients.
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Adooq Products cited in reputable paper
Science VOLUME 380, ISSUE 6663 (2023)
Science VOLUME 369, ISSUE 6510 (2020)
Science VOLUME 356, ISSUE 6336 (2017)
Cell Vol. 185 Issue 23 p4428-4447.e28
Cell Vol 177, Issue 7, p1933-1947.e25
Cell Vol 156, Issue 5, p857-1114
Nature Volume 622 Issue 7982 (2023)
Nature volume 620, pages890-897 (2023)
Nature volume 610, pages540-546 (2022)
Nature volume 588, pages83-88 (2020)
Nature volume 574, pages268-272 (2019)
Nature volume 573, pages539-545 (2019)
Nature volume 567, pages118-122 (2019)
Nature volume 551, pages639-643 (2017)
Nature volume 551, pages247-250 (2017)
Nature volume 548, pages356-360 (2017)
Nature volume 545, pages187-192 (2017)
Biological Activity
DescriptionKCa2 Channel Modulator 1 is a potent subtype-selective positive modulator specifically targeting KCa2 channels. It enhances the activity of human KCa2.3 channels with an EC50 of 0.19 μM, and also exhibits activity on rat KCa2.2 channels with an EC50 of 0.99 μM. This compound is valuable for research applications focusing on calcium-activated potassium channels and their roles in various physiological processes.
Product Information
Catalog NumA68139
FormulaC16H15ClFN5
Molecular Weight331.78
CAS Number1019106-73-0
SMILESCC1=CC(NC2=CC=C(F)C(Cl)=C2)=NC(N3N=C(C)C=C3C)=N1
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Membrane Transporters-Ion Channels > Potassium Channels