KI-7 is a positive allosteric modulator of the A2B adenosine receptor. It enhances cAMP accumulation induced by the non-selective A2B agonist NECA, with an EC50 of 445.8 nM, and also increases cAMP levels in response to the selective agonist BAY 60-6583 and adenosine, exhibiting EC50 values of 2390 nM and 2550 nM, respectively. This compound is valuable for research in adenosine receptor signaling and modulation of associated pathways.
KI-7 is a positive allosteric modulator of the A2B adenosine receptor. It enhances cAMP accumulation induced by the non-selective A2B agonist NECA, with an EC50 of 445.8 nM, and also increases cAMP levels in response to the selective agonist BAY 60-6583 and adenosine, exhibiting EC50 values of 2390 nM and 2550 nM, respectively. This compound is valuable for research in adenosine receptor signaling and modulation of associated pathways.
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