KLS-13019 is an orally active antagonist of the GPR55 receptor, structurally related to cannabidiol (CBD). This compound has demonstrated the ability to prevent and reverse chemotherapy-induced peripheral neuropathy (CIPN) in a dose-dependent manner in rat models. Its selectivity for GPR55 makes it a valuable tool for investigating the role of this receptor in neuropathic pain and related therapeutic applications.
KLS-13019 is an orally active antagonist of the GPR55 receptor, structurally related to cannabidiol (CBD). This compound has demonstrated the ability to prevent and reverse chemotherapy-induced peripheral neuropathy (CIPN) in a dose-dependent manner in rat models. Its selectivity for GPR55 makes it a valuable tool for investigating the role of this receptor in neuropathic pain and related therapeutic applications.
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