KM 11060

Catalog No.: A15843

F508del-CFTR trafficking corrector

KM 11060 Chemical Structure

CAS NO. 774549-97-2

KM 11060 corrects F508del-CFTR trafficking, increasing the amount of functional CFTR at the plasma membrane (~75%) and Inhibits PDE5 activity

Availability: In stock

Package Price Qty
10 mg
$80.00
25 mg
$170.00
50 mg
$320.00
Warning Products are for laboratory research use only. Not for human use. We do not sell to patients.

Biological Activity

KM 11060 corrects F508del-CFTR trafficking, increasing the amount of functional CFTR at the plasma membrane (~75%) and Inhibits PDE5 activity
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 23.68 mL 118.39 mL 236.78 mL
0.5 mM 4.74 mL 23.68 mL 47.36 mL
1 mM 2.37 mL 11.84 mL 23.68 mL
5 mM 0.47 mL 2.37 mL 4.74 mL

*The above data is based on the productmolecular weight 422.33. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

Catalog Num A15843
Actions No
M. Wt 422.33
Formula C19H17Cl2N3O2S
Solubility DMSO
Purity >98%
Storage at -20°C 3 years Powder
CAS No. 774549-97-2
Synonyms KM-11060, KM11060
SMILES O=S(N1CCN(C2=CC=NC3=CC(Cl)=CC=C23)CC1)(C4=CC=C(Cl)C=C4)=O

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