KMT9-IN-1 is a prodrug of the KMT9 inhibitor that releases the active compound 7b upon hydrolysis by cellular esterases. This compound effectively targets KMT9, resulting in a reduction of H4K12me1 levels. KMT9-IN-1 exhibits notable antitumor activity against colon cancer and can be employed in research focused on prostate cancer and hepatocellular carcinoma.
KMT9-IN-1 is a prodrug of the KMT9 inhibitor that releases the active compound 7b upon hydrolysis by cellular esterases. This compound effectively targets KMT9, resulting in a reduction of H4K12me1 levels. KMT9-IN-1 exhibits notable antitumor activity against colon cancer and can be employed in research focused on prostate cancer and hepatocellular carcinoma.
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