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KPLH1130 is a specific pyruvate dehydrogenase kinase (PDK) inhibitor, blocks macrophage polarization and attenuates proinflammatory responses. KPLH1130 improves glucose tolerance in HFD-fed mice.
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 0.1 mM | 35.3 mL | 176.5 mL | 353.01 mL |
| 0.5 mM | 7.06 mL | 35.3 mL | 70.6 mL |
| 1 mM | 3.53 mL | 17.65 mL | 35.3 mL |
| 5 mM | 0.71 mL | 3.53 mL | 7.06 mL |
*The above data is based on the productmolecular weight 283.28. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.
| Catalog Num | A18494 |
|---|---|
| Actions | Inhibitor |
| CAS No. | 906669-07-6 |
| Formula | C15H13N3O3 |
| M. Wt | 283.28 |
| Purity | >98% |
| Synonyms | KPLH 1130, KPLH-1130 |
| SMILES | OC1=CC=C(C2=NNC(N2C3=CC=C(C)C=C3)=O)C(O)=C1 |
| Storage | Store lyophilized at -20ºC, keep desiccated. |
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