KR-30450

Catalog No.: A68295
Potassium Channel Activator
KR-30450 is a potent potassium channel activator with a specific action as a K+ ATP opener. It demonstrates significant cardioprotective effects, outperforming Lemakalim in enhancing reperfusion cardiac function. Additionally, KR-30450 effectively reduces reperfusion contracture and the release of lactate dehydrogenase, making it valuable for research in cardiac protection and ischemia-reperfusion injury studies.
Grouped product items
Size Price Stock Qty
25mg
$1,275.00
In stock
50mg
$1,625.00
In stock
100mg
$2,000.00
In stock
Bulk Size
Bulk Discount
Free Delivery on orders over $500
Research use only. We do not sell to patients.

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Adooq Products cited in reputable paper
Science VOLUME 380, ISSUE 6663 (2023)
Science VOLUME 369, ISSUE 6510 (2020)
Science VOLUME 356, ISSUE 6336 (2017)
Cell Vol. 185 Issue 23 p4428-4447.e28
Cell Vol 177, Issue 7, p1933-1947.e25
Cell Vol 156, Issue 5, p857-1114
Nature Volume 622 Issue 7982 (2023)
Nature volume 620, pages890-897 (2023)
Nature volume 610, pages540-546 (2022)
Nature volume 588, pages83-88 (2020)
Nature volume 574, pages268-272 (2019)
Nature volume 573, pages539-545 (2019)
Nature volume 567, pages118-122 (2019)
Nature volume 551, pages639-643 (2017)
Nature volume 551, pages247-250 (2017)
Nature volume 548, pages356-360 (2017)
Nature volume 545, pages187-192 (2017)
Biological Activity
DescriptionKR-30450 is a potent potassium channel activator with a specific action as a K+ ATP opener. It demonstrates significant cardioprotective effects, outperforming Lemakalim in enhancing reperfusion cardiac function. Additionally, KR-30450 effectively reduces reperfusion contracture and the release of lactate dehydrogenase, making it valuable for research in cardiac protection and ischemia-reperfusion injury studies.
Product Information
Catalog NumA68295
FormulaC17H18N2O6
Molecular Weight346.33
CAS Number172489-10-0
SMILESO=C1N(C2=C[C@](C)(C3OCCO3)OC4=CC=C([N+]([O-])=O)C=C24)CCC1
SynonymsSKP 450
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