KRAS G12C degrader-2 is an E3 ligase ligand-linker conjugate that incorporates a CRBN-based ligand and a functional linker. This compound facilitates the development of PROTAC (proteolysis-targeting chimeras), enabling targeted degradation of KRAS G12C-mutant proteins. It is a valuable tool for researchers investigating the therapeutic potential of targeted protein degradation in cancer treatment.
KRAS G12C degrader-2 is an E3 ligase ligand-linker conjugate that incorporates a CRBN-based ligand and a functional linker. This compound facilitates the development of PROTAC (proteolysis-targeting chimeras), enabling targeted degradation of KRAS G12C-mutant proteins. It is a valuable tool for researchers investigating the therapeutic potential of targeted protein degradation in cancer treatment.
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