KRAS G12C inhibitor 16

Catalog No.: A18444

KRAS G12C inhibitor

KRAS G12C inhibitor 16

KRAS G12C inhibitor 16 Chemical Structure

CAS NO. 2349392-79-4

KRAS G12C inhibitor 16 is a potent KRAS G12C inhibitor extracted from patent WO2019110751A1, compound 39, has an IC50 of 97 nM.

Availability: In stock

Package Price Qty
1 mg
$320.00
5 mg
$960.00
10 mg
$1,600.00
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Biological Activity

KRAS G12C inhibitor 16 is a potent KRAS G12C inhibitor extracted from patent WO2019110751A1, compound 39, has an IC50 of 97 nM.
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 22.03 mL 110.16 mL 220.32 mL
0.5 mM 4.41 mL 22.03 mL 44.06 mL
1 mM 2.2 mL 11.02 mL 22.03 mL
5 mM 0.44 mL 2.2 mL 4.41 mL

*The above data is based on the productmolecular weight 453.89. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

Catalog Num A18444
Actions Inhibitor
CAS No. 2349392-79-4
Formula C24H21ClFN3O3
M. Wt 453.89
Purity >98%
SMILES OC1=C(C2=C(C)C(N=CC3=C4N5[[email protected]](CN(C(C=C)=O)CC5)CO3)=C4C=C2Cl)C(F)=CC=C1
Storage

Store lyophilized at -20ºC, keep desiccated.
In lyophilized form, the chemical is stable for 36 months.
In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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