KRAS G12C inhibitor 17

Catalog No.: A18441

KRAS G12C inhibitor

KRAS G12C inhibitor 17

KRAS G12C inhibitor 17 Chemical Structure

CAS NO. 2349393-04-8

KRAS G12C inhibitor 17 is a potent KRAS G12C inhibitor extracted from patent WO2019110751A1, compound 82, has an IC50 of 5 nM.

Availability: In stock

Package Price Qty
1 mg
$320.00
5 mg
$960.00
10 mg
$1,600.00
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Biological Activity

KRAS G12C inhibitor 17 is a potent KRAS G12C inhibitor extracted from patent WO2019110751A1, compound 82, has an IC50 of 5 nM.
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 21.19 mL 105.96 mL 211.92 mL
0.5 mM 4.24 mL 21.19 mL 42.38 mL
1 mM 2.12 mL 10.6 mL 21.19 mL
5 mM 0.42 mL 2.12 mL 4.24 mL

*The above data is based on the productmolecular weight 471.88. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

Catalog Num A18441
Actions Inhibitor
CAS No. 2349393-04-8
Formula C24H20ClF2N3O3
M. Wt 471.88
Solubility DMSO
Purity >98%
SMILES FC1=CC=CC(O)=C1C2=C(F)C(N=CC3=C4N5[[email protected]](CN(C(C=C)=O)[[email protected]](C)C5)CO3)=C4C=C2Cl
Storage

Store lyophilized at -20ºC, keep desiccated.
In lyophilized form, the chemical is stable for 36 months.
In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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