KRX-0402

Catalog No.: A15459

DNA repair inhibitor

KRX-0402

KRX-0402 Chemical Structure

CAS NO. 1000874-21-4

KRX-0402 is a small molecule that was specifically designed to block the DNA repair protein, MGMT. MGMT confers resistance to certain alkylating agents, such as temozolomide and BCNU, that are commonly used to treat brain cancer, melanoma and non-Hodgkin’s lymphoma.

Availability: In stock

Package Price Qty
5 mg
$150.00
10 mg
$280.00
25 mg
$550.00
Custom Size Get quote

Free Overnight Delivery on orders over $500

Next day delivery by 10:00 a.m. Order now.

Warning Products are for laboratory research use only. Not for human use. We do not sell to patients.

Biological Activity

KRX-0402 is a small molecule that was specifically designed to block the DNA repair protein, MGMT. MGMT confers resistance to certain alkylating agents, such as temozolomide and BCNU, that are commonly used to treat brain cancer, melanoma and non-Hodgkin’s lymphoma.
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 41.45 mL 207.25 mL 414.51 mL
0.5 mM 8.29 mL 41.45 mL 82.9 mL
1 mM 4.15 mL 20.73 mL 41.45 mL
5 mM 0.83 mL 4.15 mL 8.29 mL

*The above data is based on the productmolecular weight 241.25. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

Catalog Num A15459
Actions Inhibitor
CAS No. 1000874-21-4
Formula C12H11N5O
M. Wt 241.25
Purity >98%
Synonyms O6-benzyl guanine, O6-BG
SMILES NC1=NC(OCC2=CC=CC=C2)=C3NC=NC3=N1
Storage

Store lyophilized at -20ºC, keep desiccated.
In lyophilized form, the chemical is stable for 36 months.
In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

Product Tags

Product Tags

Use spaces to separate tags. Use single quotes (') for phrases.

Product Questions

Product Questions

No Questions
Keywords:buy KRX-0402 | KRX-0402 Supplier | purchase | cost | manufacturer | order | distributor | buy 1000874-21-4| 1000874-21-4 Supplier | purchase 1000874-21-4 | 1000874-21-4 cost | 1000874-21-4 manufacturer | order 1000874-21-4 | 1000874-21-4 distributor
Rewards