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KTX-582 intermediate-1

Catalog No.: A31483
Intermediate
KTX-582 intermediate-1 is a crucial intermediate in the synthesis of KTX-582, serving as a key component for antibody-drug conjugate (ADC) preparation. KTX-582 functions as an IRAK4 degrader, effectively inducing apoptosis with DC50 values of 4 nM for IRAK4 and 5 nM for Ikaros. This compound is instrumental for research applications focused on targeting IRAK4-related pathways and exploring therapeutic strategies in various cancers.
KTX-582 intermediate-1 845508-29-4 Intermediate
Grouped product items
Size Price Stock Qty
5mg
$40.00
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10mg
$60.00
In stock
25mg
$110.00
In stock
50mg
$150.00
In stock
100mg
$200.00
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Research use only. We do not sell to patients.
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Adooq Products cited in reputable paper
Science VOLUME 380, ISSUE 6663 (2023)
Science VOLUME 369, ISSUE 6510 (2020)
Science VOLUME 356, ISSUE 6336 (2017)
Cell Vol. 185 Issue 23 p4428-4447.e28
Cell Vol 177, Issue 7, p1933-1947.e25
Cell Vol 156, Issue 5, p857-1114
Nature Volume 622 Issue 7982 (2023)
Nature volume 620, pages890-897 (2023)
Nature volume 610, pages540-546 (2022)
Nature volume 588, pages83-88 (2020)
Nature volume 574, pages268-272 (2019)
Nature volume 573, pages539-545 (2019)
Nature volume 567, pages118-122 (2019)
Nature volume 551, pages639-643 (2017)
Nature volume 551, pages247-250 (2017)
Nature volume 548, pages356-360 (2017)
Nature volume 545, pages187-192 (2017)
Biological Activity
DescriptionKTX-582 intermediate-1 is a crucial intermediate in the synthesis of KTX-582, serving as a key component for antibody-drug conjugate (ADC) preparation. KTX-582 functions as an IRAK4 degrader, effectively inducing apoptosis with DC50 values of 4 nM for IRAK4 and 5 nM for Ikaros. This compound is instrumental for research applications focused on targeting IRAK4-related pathways and exploring therapeutic strategies in various cancers.
Product Information
Catalog NumA31483
FormulaC16H22O5S
Molecular Weight326.41
CAS Number845508-29-4
SMILESCCOC([C@@H](CC1)CC[C@@H]1OS(=O)(C2=CC=C(C=C2)C)=O)=O
Useful Calculator

This calculator helps you calculate mass of compound based on solution concentration, volume and molecular weight in a specific solution using the formula:

Mass (mg) = Concentration (mM) × Volume (mL) × Molecular Weight (g/mol)

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Please check COA/MSDS for correct molecular weight.

Calculate the dilution required to prepare a stock solution.
This equation is commonly abbreviated as: C1V1 = C2V2

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Protein Tyrosine Kinases > IRAK