KU-0063794

Catalog No.: A10505

mTOR Inhibitor

KU-0063794

KU-0063794 Chemical Structure

CAS NO. 938440-64-3

KU-0063794 is a selective inhibitor of mammalian target of rapamycin (mTOR) (IC50 ~10 nM for mTORC1 and mTORC2 respectively).

Availability: In stock

Package Price Qty
5 mg

Regular Price: $50.00

Special Price $45.00

25 mg

Regular Price: $150.00

Special Price $135.00

50 mg

Regular Price: $220.00

Special Price $198.00

100 mg

Regular Price: $400.00

Special Price $360.00

10mM * 1mL in DMSO

Regular Price: $50.00

Special Price $45.00

Warning Products are for laboratory research use only. Not for human use. We do not sell to patients.

Biological Activity

KU-0063794 is a selective inhibitor of mammalian target of rapamycin (mTOR) (IC50 ~10 nM for mTORC1 and mTORC2 respectively).
Targets
mTORC1 (Cell-free assay) mTORC2 (Cell-free assay)
~10 nM~10 nM
In vitro (25°C) DMSO 16 mg/mL (34.36 mM)
Water <1 mg/mL (<1 mM)
Ethanol <1 mg/mL (<1 mM)
In vivo 30% PEG400/0.5% Tween80/5% propylene glycol 30 mg/mL
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 21.48 mL 107.41 mL 214.82 mL
0.5 mM 4.3 mL 21.48 mL 42.96 mL
1 mM 2.15 mL 10.74 mL 21.48 mL
5 mM 0.43 mL 2.15 mL 4.3 mL

*The above data is based on the productmolecular weight 465.5 . Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

Chemical Properties

Catalog Num A10505
Actions Inhibitor
M. Wt 465.5
Formula C25H31N5O4
Solubility DMSO
Purity >98%
Storage at -20°C 3 years Powder
CAS No. 938440-64-3
Synonyms KU0063794
SMILES C[[email protected]@H]1CN(C[[email protected]@H](O1)C)C2=NC3=C(C=CC(=N3)C4=CC(=C(C=C4)OC)CO)C(=N2)N5CCOCC5

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