KV1.3-IN-1 is a selective inhibitor of the KV1.3 potassium channel, exhibiting IC50 values of 230 nM in Ltk cells and 26.12 nM in PHA-activated T-lymphocytes. This compound disrupts intracellular Ca2+ signaling, leading to notable inhibition of T-cell activation, proliferation, and colony formation. KV1.3-IN-1 is an essential tool for research on T-cell biology and the modulation of immune responses.
KV1.3-IN-1 is a selective inhibitor of the KV1.3 potassium channel, exhibiting IC50 values of 230 nM in Ltk cells and 26.12 nM in PHA-activated T-lymphocytes. This compound disrupts intracellular Ca2+ signaling, leading to notable inhibition of T-cell activation, proliferation, and colony formation. KV1.3-IN-1 is an essential tool for research on T-cell biology and the modulation of immune responses.
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