KVI-020 is a potent and selective blocker of the atrial potassium channel Kv1.5, exhibiting an IC50 of 480 nM. This compound demonstrates a weaker inhibition of hERG channels, with an IC50 of 15,100 nM. KVI-020 serves as an effective antiarrhythmic agent and is valuable for research focused on atrial fibrillation (AF) and related cardiac dysrhythmias.
KVI-020 is a potent and selective blocker of the atrial potassium channel Kv1.5, exhibiting an IC50 of 480 nM. This compound demonstrates a weaker inhibition of hERG channels, with an IC50 of 15,100 nM. KVI-020 serves as an effective antiarrhythmic agent and is valuable for research focused on atrial fibrillation (AF) and related cardiac dysrhythmias.
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