L 651142 is a weak antagonist of the platelet activating factor (PAF) receptor. This compound effectively inhibits the binding of [3H]PAF to membranes derived from rabbit platelets, human platelets, and human lung tissues, with inhibition constants (Kis) of 0.839 μM, 1.82 μM, and 3.64 μM, respectively. L 651142 is utilized in research applications that explore the role of PAF in physiological and pathological processes, making it valuable for studies related to inflammation, thrombosis, and respiratory function.
L 651142 is a weak antagonist of the platelet activating factor (PAF) receptor. This compound effectively inhibits the binding of [3H]PAF to membranes derived from rabbit platelets, human platelets, and human lung tissues, with inhibition constants (Kis) of 0.839 μM, 1.82 μM, and 3.64 μM, respectively. L 651142 is utilized in research applications that explore the role of PAF in physiological and pathological processes, making it valuable for studies related to inflammation, thrombosis, and respiratory function.
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