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L-739758

Catalog No.: A57561
Integrin Anatgonist
L-739758 is an antagonist of the αIIbβ3 integrin, also known as platelet glycoprotein IIb/IIIa. This peptidomimetic compound mimics the RGD (arginine-glycine-aspartic acid) motif, effectively binding to αIIbβ3 integrin and interfering with the blood coagulation process. L-739758 inhibits platelet aggregation, making it valuable for research focused on thrombosis and related cardiovascular disorders.
L-739758 168157-33-3 Integrin Anatgonist
Grouped product items
Size Price Stock Qty
25mg
$1,655.00
In stock
50mg
$2,115.00
In stock
100mg
$2,720.00
In stock
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Research use only. We do not sell to patients.
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Adooq Products cited in reputable paper
Science VOLUME 380, ISSUE 6663 (2023)
Science VOLUME 369, ISSUE 6510 (2020)
Science VOLUME 356, ISSUE 6336 (2017)
Cell Vol. 185 Issue 23 p4428-4447.e28
Cell Vol 177, Issue 7, p1933-1947.e25
Cell Vol 156, Issue 5, p857-1114
Nature Volume 622 Issue 7982 (2023)
Nature volume 620, pages890-897 (2023)
Nature volume 610, pages540-546 (2022)
Nature volume 588, pages83-88 (2020)
Nature volume 574, pages268-272 (2019)
Nature volume 573, pages539-545 (2019)
Nature volume 567, pages118-122 (2019)
Nature volume 551, pages639-643 (2017)
Nature volume 551, pages247-250 (2017)
Nature volume 548, pages356-360 (2017)
Nature volume 545, pages187-192 (2017)
Biological Activity
DescriptionL-739758 is an antagonist of the αIIbβ3 integrin, also known as platelet glycoprotein IIb/IIIa. This peptidomimetic compound mimics the RGD (arginine-glycine-aspartic acid) motif, effectively binding to αIIbβ3 integrin and interfering with the blood coagulation process. L-739758 inhibits platelet aggregation, making it valuable for research focused on thrombosis and related cardiovascular disorders.
Product Information
Catalog NumA57561
FormulaC22H26N4O5S3
Molecular Weight522.66
CAS Number168157-33-3
SMILESO=C([C@H](CNC(C1=CC2=C(SC(CCC3CCNCC3)=C2)S1)=O)NS(=O)(C4=CC=CN=C4)=O)O
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Cytoskeleton > Integrin