Lacidipine-13C8 is a deuterium-labeled derivative of Lacidipine, a highly selective L-type calcium channel blocker that primarily targets smooth muscle cells. This compound is known for its ability to dilate peripheral arteries, thereby reducing peripheral resistance and providing sustained antihypertensive effects. Lacidipine has also demonstrated protective effects on human kidney cells by modulating the caspase-3 pathway in response to ATP depletion. It is applicable in research related to hypertension, atherosclerosis, and acute kidney injury (AKI).
Lacidipine-13C8 is a deuterium-labeled derivative of Lacidipine, a highly selective L-type calcium channel blocker that primarily targets smooth muscle cells. This compound is known for its ability to dilate peripheral arteries, thereby reducing peripheral resistance and providing sustained antihypertensive effects. Lacidipine has also demonstrated protective effects on human kidney cells by modulating the caspase-3 pathway in response to ATP depletion. It is applicable in research related to hypertension, atherosclerosis, and acute kidney injury (AKI).
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