Lapatinib-d7 is a deuterated analog of Lapatinib, primarily targeting the ErbB-2 and EGFR tyrosine kinase domains. It exhibits potent inhibition with IC50 values of 10.2 nM and 9.8 nM for EGFR and ErbB-2, respectively. This stable isotope-labeled compound is ideal for pharmacokinetic studies and metabolic profiling in research applications related to cancer therapeutics and drug metabolism.
Lapatinib-d7 is a deuterated analog of Lapatinib, primarily targeting the ErbB-2 and EGFR tyrosine kinase domains. It exhibits potent inhibition with IC50 values of 10.2 nM and 9.8 nM for EGFR and ErbB-2, respectively. This stable isotope-labeled compound is ideal for pharmacokinetic studies and metabolic profiling in research applications related to cancer therapeutics and drug metabolism.
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