LDE225 Diphosphate

Catalog No.: A12774

Smoothened Inhibitor

LDE225 Diphosphate

LDE225 Diphosphate Chemical Structure

CAS NO. 1218778-77-8

LDE225 is an orally bioavailable small-molecule Smoothened (Smo) antagonist with potential antineoplastic activity.

Availability: In stock

Package Price Qty
5 mg

Regular Price: $45.00

Special Price $40.50

10 mg

Regular Price: $60.00

Special Price $54.00

25 mg

Regular Price: $85.00

Special Price $76.50

50 mg

Regular Price: $130.00

Special Price $117.00

Warning Products are for laboratory research use only. Not for human use. We do not sell to patients.

Biological Activity

LDE225 is an orally bioavailable small-molecule Smoothened (Smo) antagonist with potential antineoplastic activity.
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 14.67 mL 73.37 mL 146.74 mL
0.5 mM 2.93 mL 14.67 mL 29.35 mL
1 mM 1.47 mL 7.34 mL 14.67 mL
5 mM 0.29 mL 1.47 mL 2.93 mL

*The above data is based on the productmolecular weight 681.49. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

Chemical Properties

Catalog Num A12774
Actions Inhibitor
M. Wt 681.49
Formula C26H32F3N3O11P2
Solubility DMSO
Purity >98%
Storage at -20°C 3 years Powder
CAS No. 1218778-77-8
Synonyms LDE-225, LDE 225
SMILES C[[email protected]@H]1CN(C[[email protected]@H](O1)C)C2=NC=C(C=C2)NC(=O)C3=CC=CC(=C3C)C4=CC=C(C=C4)OC(F)(F)F.OP(=O)(O)O.OP(=O)(O)O

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