LEB-03-153 is a WEE1 deubiquitinase-targeting chimera (DUBTAC) designed to effectively recruit OTUB1 to the WEE1 protein via a novel mechanism. This compound facilitates the modulation of WEE1 activity, potentially influencing cell cycle progression and enhancing the therapeutic effects of AZD1775 (Adavosertib). LEB-03-153 is ideal for research applications involving cancer biology, particularly in studies focused on checkpoint regulation and therapeutic resistance.
LEB-03-153 is a WEE1 deubiquitinase-targeting chimera (DUBTAC) designed to effectively recruit OTUB1 to the WEE1 protein via a novel mechanism. This compound facilitates the modulation of WEE1 activity, potentially influencing cell cycle progression and enhancing the therapeutic effects of AZD1775 (Adavosertib). LEB-03-153 is ideal for research applications involving cancer biology, particularly in studies focused on checkpoint regulation and therapeutic resistance.
This calculator helps you calculate mass of compound based on solution concentration, volume and molecular weight in a specific solution using the formula:
