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LEE011 (Ribociclib)


CDK4/6 inhibitor

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Catalog No. A13549

Availability:Stock in USAIn stock

Product Name Catalog No. Price Qty
LEE011 10mg A13549-10

Regular Price: €76.00

Special Price: €68.40

LEE011 25mg A13549-25

Regular Price: €114.00

Special Price: €102.60

LEE011 50mg A13549-50

Regular Price: €142.50

Special Price: €128.25

Products are for laboratory research use only. Not for human use. We do not sell to patients.

Quick Overview

LEE011 is an orally available cyclin-dependent kinase (CDK) inhibitor targeting cyclin D1/CDK4 and cyclin D3/CDK6 cell cycle pathway, with potential antineoplastic activity.

LEE011 (Ribociclib)

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Chemical Information

Catalog Num A13549
Actions Inhibitor
M. Wt 434.54
Formula C23H30N8O
Solubility DMSO
Purity >98%
Storage at -20°C 3 years Powder
CAS No. 1211441-98-3
Synonyms LEE-011, LEE 011

Biological Activity

LEE011 is an orally available cyclin-dependent kinase (CDK) inhibitor targeting cyclin D1/CDK4 and cyclin D3/CDK6 cell cycle pathway, with potential antineoplastic activity.
CDK4 (Cell-free assay) CDK6 (Cell-free assay)


Solubility (25°C)* In vitro DMSO 7 mg/mL (16.1 mM)
Water <1 mg/mL (<1 mM)
Ethanol <1 mg/mL (<1 mM)
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.

Preparing Stock Solutions

Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 23.01 mL 115.06 mL 230.13mL
0.5 mM 4.6 mL 23.01 mL 46.03 mL
1 mM 2.3 mL 11.51 mL 23.01 mL
5 mM 0.46 mL 2.3 mL 4.6 mL

*The above data is based on the productmolecular weight 434.54. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

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