LEI-401

Catalog No.: A77100
NAPE-PLD Inhibitor
LEI-401 is a selective inhibitor of N-acylphosphatidylethanolamine phospholipase D (NAPE-PLD), exhibiting an IC50 of 27 nM. This CNS-active compound has been shown to modulate emotional behavior in mice, making it a valuable tool for research into neurochemistry and behavioral science. Its unique mechanism of action positions LEI-401 as a candidate for exploring therapeutic pathways in mood disorders and related conditions.
Grouped product items
Size Price Stock Qty
1mg
$40.00
In stock
5mg
$125.00
In stock
10mg
$185.00
In stock
25mg
$380.00
In stock
50mg
$630.00
In stock
100mg
$1,080.00
In stock
Bulk Size
Bulk Discount
Free Delivery on orders over $500
Research use only. We do not sell to patients.

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Adooq Products cited in reputable paper
Science VOLUME 380, ISSUE 6663 (2023)
Science VOLUME 369, ISSUE 6510 (2020)
Science VOLUME 356, ISSUE 6336 (2017)
Cell Vol. 185 Issue 23 p4428-4447.e28
Cell Vol 177, Issue 7, p1933-1947.e25
Cell Vol 156, Issue 5, p857-1114
Nature Volume 622 Issue 7982 (2023)
Nature volume 620, pages890-897 (2023)
Nature volume 610, pages540-546 (2022)
Nature volume 588, pages83-88 (2020)
Nature volume 574, pages268-272 (2019)
Nature volume 573, pages539-545 (2019)
Nature volume 567, pages118-122 (2019)
Nature volume 551, pages639-643 (2017)
Nature volume 551, pages247-250 (2017)
Nature volume 548, pages356-360 (2017)
Nature volume 545, pages187-192 (2017)
Biological Activity
DescriptionLEI-401 is a selective inhibitor of N-acylphosphatidylethanolamine phospholipase D (NAPE-PLD), exhibiting an IC50 of 27 nM. This CNS-active compound has been shown to modulate emotional behavior in mice, making it a valuable tool for research into neurochemistry and behavioral science. Its unique mechanism of action positions LEI-401 as a candidate for exploring therapeutic pathways in mood disorders and related conditions.
Product Information
Catalog NumA77100
FormulaC24H31N5O2
Molecular Weight421.54
CAS Number2393840-15-6
SMILESO=C(C1=NC(N2C[C@H](C3=CC=CC=C3)CCC2)=NC(N4C[C@@H](O)CC4)=C1)NCC5CC5
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