Lenalidomide 5'-piperazine-C1-piperidine

Catalog No.: A80441
E3 Ligase Ligand-Linker Conjugate
Lenalidomide 5'-piperazine-C1-piperidine is an E3 ligase ligand-linker conjugate that features a CRBN-based ligand coupled with a linker moiety. This compound is designed for the synthesis of PROTACs (Proteolysis Targeting Chimeras), facilitating targeted protein degradation. Its primary application lies in the study and modulation of protein levels in various biological contexts, making it an essential tool for cancer research and drug discovery.
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Adooq Products cited in reputable paper
Science VOLUME 380, ISSUE 6663 (2023)
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Cell Vol 177, Issue 7, p1933-1947.e25
Cell Vol 156, Issue 5, p857-1114
Nature Volume 622 Issue 7982 (2023)
Nature volume 620, pages890-897 (2023)
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Nature volume 574, pages268-272 (2019)
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Nature volume 551, pages639-643 (2017)
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Biological Activity
DescriptionLenalidomide 5'-piperazine-C1-piperidine is an E3 ligase ligand-linker conjugate that features a CRBN-based ligand coupled with a linker moiety. This compound is designed for the synthesis of PROTACs (Proteolysis Targeting Chimeras), facilitating targeted protein degradation. Its primary application lies in the study and modulation of protein levels in various biological contexts, making it an essential tool for cancer research and drug discovery.
Product Information
Catalog NumA80441
FormulaC23H31N5O3
Molecular Weight425.53
CAS Number2520105-46-6
SMILESO=C1NC(=O)C(N2C(=O)C3=CC=C(C=C3C2)N4CCN(CC4)CC5CCNCC5)CC1
Useful Calculator

This calculator helps you calculate mass of compound based on solution concentration, volume and molecular weight in a specific solution using the formula:

Mass (mg) = Concentration (mM) × Volume (mL) × Molecular Weight (g/mol)

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Please check COA/MSDS for correct molecular weight.

Calculate the dilution required to prepare a stock solution.
This equation is commonly abbreviated as: C1V1 = C2V2

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