Lenalidomide-OH is a potent analog of the cereblon (CRBN) ligand Lenalidomide, designed to selectively engage E3 ubiquitin ligase. This compound facilitates the recruitment of CRBN protein, essential for targeted protein degradation applications. Lenalidomide-OH can be coupled with various ligands via a linker to construct PROTACs, such as the BTK degrader SJF620, making it a valuable tool in studies of protein homeostasis and therapeutic development.
Lenalidomide-OH is a potent analog of the cereblon (CRBN) ligand Lenalidomide, designed to selectively engage E3 ubiquitin ligase. This compound facilitates the recruitment of CRBN protein, essential for targeted protein degradation applications. Lenalidomide-OH can be coupled with various ligands via a linker to construct PROTACs, such as the BTK degrader SJF620, making it a valuable tool in studies of protein homeostasis and therapeutic development.
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