Lenalidomide-Pip-butyn is an E3 ligase ligand-linker conjugate derived from Lenalidomide. It effectively recruits the CRBN protein, facilitating targeted protein degradation through the formation of proteolysis-targeting chimeras (PROTACs). This reagent is particularly useful for creating PROTACs like the STAT3 degrader SD-436, enabling studies on protein regulation and degradation pathways in cellular models.
Lenalidomide-Pip-butyn is an E3 ligase ligand-linker conjugate derived from Lenalidomide. It effectively recruits the CRBN protein, facilitating targeted protein degradation through the formation of proteolysis-targeting chimeras (PROTACs). This reagent is particularly useful for creating PROTACs like the STAT3 degrader SD-436, enabling studies on protein regulation and degradation pathways in cellular models.
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